Some Governor with a.working testicle needs to order Nat Guard to shoot it down as it crosses their state.
At that altitude do you have any idea how diffused anything inside would be before it hit the ground? Not even talking about UV destruction on the way down.
An aerosolized weapon deployed at that altitude would do nothing.
Send in the BRRRRRT!
Inspection teams would likely be HAZMAT equipped.
It would be a cool nod to anons. We love our hogs.