after compromising their immune systems with vaids/ade
https://www.wkbn.com/news/local-news/east-palestine-train-derailment/3-additional-chemicals-discovered-on-east-palestine-train-derailment/
3 additional chemicals discovered on East Palestine train derailment
EAST PALESTINE, Ohio (WKBN) ā First News was recently informed of three more chemicals that were on the Norfolk Southern train that derailed in East Palestine just over a week ago ā and we are being told that those chemicals are dangerous.
āWe basically nuked a town with chemicals so we could get a railroad open,ā said Silverado Caggiano, a hazardous materials specialist.
East Palestine water quality testing continues
The U.S. Environmental Protection Agency sent a letter to Norfolk Southern stating thatethylene glycol monobutyl ether, ethylhexyl acrylate and isobutylenewere also in the rail cars that were derailed, breached and/or on fire.
Caggiano says ethylhexyl acrylate is especially worrisome. He says itās a carcinogen and contact with it can cause burning and irritation in the skin and eyes. Breathing it in can irritate the nose and throat and cause coughing and shortness of breath.
Isobutylene is also known to cause dizziness and drowsiness when inhaled.
āI was surprised when they quickly told the people they can go back home, but then said if they feel like they want their homes tested they can have them tested. I wouldāve far rather they did all the testing,ā Caggiano said.
Caggiano says itās possible some of these chemicals could still be present in homes and on objects until you clean them thoroughly.
āThereās a lot of what ifs, and weāre going to be looking at this thing 5, 10, 15, 20 years down the line and wondering, āGee, cancer clusters could pop up, you know, well water could go bad,ā Caggiano said.
Caggiano recommends anyone in the East Palestine area should get a health check-up. Get it on record where your health stands now so that moving forward youāll have documented any effects possibly related to the train derailment.
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https://www.darpa.mil/news-events/2017-02-06a
Removing the Viral Threat: Two Months to Stop Pandemic X from Taking Hold
DARPA aims to develop an integrated end-to-end platform that uses nucleic acid sequences to halt the spread of viral infections in sixty days or less
Over the past several years, DARPA-funded researchers have pioneered RNA vaccine technology, a medical countermeasure against infectious diseases that uses coded genetic constructs to stimulate production of viral proteins in the body, which in turn can trigger a protective antibody response. As a follow-on effort, DARPA funded research into genetic constructs that can directly stimulate production of antibodies in the body.1,2 DARPA is now launching the Pandemic Prevention Platform (P3) program, aimed at developing that foundational work into an entire system capable of halting the spread of any viral disease outbreak before it can escalate to pandemic status. Such a capability would offer a stark contrast to the state of the art for developing and deploying traditional vaccinesāa process that does not deliver treatments to patients until months, years, or even decades after a viral threat emerges.
āDARPAās goal is to create a technology platform that can place a protective treatment into health providersā hands within 60 days of a pathogen being identified, and have that treatment induce protection in patients within three days of administration. We need to be able to move at this speed considering how quickly outbreaks can get out of control,ā said Matt Hepburn, the P3 Program Manager. āThe technology needs to work on any viral disease, whether itās one humans have faced before or not.ā
Recent outbreaks of viral infectious diseases such as Zika, H1N1 influenza, and Ebola have cast into sharp relief the inability of the global health system to rapidly contain the spread of a disease using existing tools and procedures. State-of-the-art medical countermeasures typically take many months or even years to develop, produce, distribute, and administer. These solutions often arrive too lateāif at allāand in quantities too small to respond to emerging threats. In contrast, the envisioned P3 platform would cut response time to weeks and stay within the window of relevance for containing an outbreak.
Key to this undertaking are nucleic-acid-based technologiesāthose that are centered on DNA and RNAāincluding some developed under DARPAās Autonomous Diagnostics to Enable Prevention and Therapeutics (ADEPT) program. Using these tools, scientists can identify protective antibodies from recovering patients and then, through a biological version of reverse engineering, manufacture genetic constructs that, when delivered, can instruct an individualās body to produce similar protective antibodies. Significant quantities of these nucleic acid āblueprintsā can be rapidly manufactured compared to state-of-the-art antibody production methods.
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What is required now are breakthroughs in three other technology areas to bridge those past DARPA achievements and overcome the remaining bottlenecks that hinder rapid response to pandemic threats. The P3 program will pursue innovations in those three areas:
Growing virus needed to support evaluation of therapies in laboratory tests;
Subjecting antibodies to rapid rounds of evolution outside of the body to increase their potency beyond that of even the most effective antibodies obtained from infected patients; and
Developing means of efficiently delivering nucleic-acid-based protective treatments, since the technologies used to administer conventional vaccines do not readily translate.
Achieving and integrating breakthroughs in all of these areas will require choreographed cooperation among researchers and engineers specializing in such areas as immunology, microbiology, virology, medical infectious diseases, molecular biology, and medical countermeasure product development and manufacturing.
DARPA-funded teams will be required to demonstrate their integrated platforms in five simulations during the planned four-year program; they will initially test their platforms using pathogens of their choice, but ultimately they will test using DARPA-selected pathogens, including two demonstrations in which the identity of the pathogen will remain opaque to the teams until the 60-day clock starts. To ensure the developed platforms can produce a quality product with a viable pathway for regulatory review, each team will be required to complete a Phase I clinical safety trial before the end of the program.
A benefit of the nucleic-acid-based approach to limiting the spread of infection is that the genetic constructs introduced to the body would be processed quickly and would not integrate into an individualās genome. Similarly, the antibodies produced in response to the treatment would only be present in the body for weeks to months. This is consistent with DARPA's intent with P3, which is to safely deliver transient immunity to a virus, halting the spread of disease by creating a firewall.
āOur country asks our military Service members to deploy globally and provide humanitarian assistance in all manner of high-risk environments. We owe it to them to develop the best protections possible,ā said Hepburn, a U.S. Army physician who previously served as Director of Medical Preparedness on the White House National Security Staff. āIf weāre successful, DARPA could take viral infectious disease outbreaks off the table as a threat to U.S. troops and as a driver of global instability.ā
To further clarify the P3 program vision, answer questions from potential proposers, and facilitate teaming, DARPA is hosting two identical Proposers Days. The first will be at the Crown Plaza Tysons Corner McLean Hotel in McLean, Va., on February 22, 2017, and the second at the Doubletree by Hilton Hotel San Diego Downtown in San Diego on March 2, 2017. For registration information, visit: http://www.cvent.com/d/9vqy52.
Full details of the P3 program are included in a Broad Agency Announcement, available at: http://go.usa.gov/x9FbG. Proposal abstracts are due by 12:00 PM ET on March 13, 2017. Full proposals are due by 5:00 PM ET on May 1, 2017.
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Image caption: The Pandemic Prevention Platform (P3) program aims to develop an integrated platform that uses nucleic acid sequences to halt the spread of viral infections in sixty days or less. Using nucleic-acid-based technologies pioneered by DARPA as a foundation, the program now seeks to create an end-to-end platform by developing technologies to overcome remaining bottlenecks that hinder rapid response to pandemic threats. The three required technology areas cover growth of virus to support testing of treatments; rapid evolution of protective antibodies outside of the body; and safe and efficient delivery of nucleic-acid-based protective treatments.
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