Vaccines aren’t suitable for coronaviruses.

Fauci in his article in Cell—“Rethinking next-generation vaccines for coronaviruses, influenzaviruses, and other respiratory viruses”

states it as plainly as possible: the COVID-19 vaccine didn’t work because it couldn’t work.

Vaccines aren’t suitable for coronaviruses. Such respiratory viruses spread and mutate too quickly. This is why there has never been a vaccine for the common cold and why the flu shot is predictably suboptimal. Vaccines can only be sterilizing and contribute to public health when the virus is a stable pathogen, such as smallpox and measles. For coronaviruses, there’s really only one way forward: better antivirals, therapeutics, and acquired immunity.

https://www.cell.com/action/showPdf?pii=S1931-3128%2822%2900572-8

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