Anonymous ID: 80be5e March 9, 2023, 7:33 a.m. No.18473698   🗄️.is 🔗kun   >>3731 >>3769 >>3805 >>4013 >>4278 >>4311

https://mobile.twitter.com/JoshWalkos/status/1633120833903132674

 

Champagne Joshi

@JoshWalkos

·

Mar 7

A newly obtained 2,237 page Pfizer report obtained by

@ICANdecide

looking at dose dependent toxicity in rats found:

 

• Enlarged spleens

•Enlarged adrenal glands

•Enlarged lymph nodes

•Kidney and liver congestion

•Increased fibrinogen

It was a only 6 week study.

Champagne Joshi

@JoshWalkos

·

Mar 7

Despite the following Pfizer couched these obvious concerns as a no biggie. It’s almost as if they knew their product was going to be approved no matter what.

 

“All of these issues clearly show effects beyond the injection site. Of particular concern is the increased fibrinogen… Show more

Champagne Joshi

@JoshWalkos

·

Mar 7

“With regard to deaths, the report indicated that “[n]o test item-related deaths were noted for any treatment” and that “no premature deaths occurred and no premature sacrifice was necessary.” That seems reassuring, right? It only took slightly closer reading to discover,… Show more

Champagne Joshi

@JoshWalkos

·

Mar 7

Link to full report in the article:

icandecide.org

ICAN’s Attorneys Uncover Early Pfizer Vaccine Study Revealing Alarming Systemic Reactions in Rats -…

This month, ICAN’s attorneys reviewed a startling 2,237-page report from June 2020 (amended in September 2020) that Pfizer submitted to the FDA concerning its mRNA COVID-19 vaccine.

Ehden (#PfizerLeak/#MonkeyBusiness/#COptiGate)

@eh_den

·

Mar 7

Replying to

@JoshWalkos

Since the rats used by Pfizer in their repeat dose toxicity study had ACE2 receptors that prevented effective binding of the spike protein, the results are most likely a demonstration to the high toxicity of the lipid nano particles (LNP) used by Pfizer.

ehden.substack.com

The Rats

THE ULTIMATE PROOF THAT Pfizer/BioNTech NEVER DEMONSTRATED THEIR COVID19 "VACCINES" ARE SAFE OR EFFECTIVE, AND HOW HEALTH REGULATORS AROUND THE WORLD COLLUDED WITH THEM.

Champagne Joshi

@JoshWalkos

Replying to

@eh_den

Yea this is yet another aspect that no one really discuses outside of our little twitterverse. The LNP is highly inflammatory and goes all over the body. They knew this bc LNPs were designed specifically to cross the BBB in brain tumor patients.

 

Another aspect that gets little if any discussion is the non-natural RNA nucleobase N1-methylpseudouridine ( m1Ψ ) which enhances immune evasion and protein production. It’s the forgotten ingredient for some reason. Studied very little prior to mass use and just rollled out bc it stabilizes the payload.

 

The combo of the LNP, S producing mRNA, and m1Ψ are the perfect bioweapon. Unfortunately.

Anonymous ID: 80be5e March 9, 2023, 7:50 a.m. No.18473769   🗄️.is 🔗kun

>>18473698

some responses

 

Guillaume

@Guillau13441190

·

Mar 7

Replying to

@JoshWalkos

and

@eh_den

Absolutly. The perfect one.

NB : LNP biodistribution was known since 2014 by Novartis.

Matthew B

@Wontevertweet27

·

Mar 7

Replying to

@JoshWalkos

and

@eh_den

What's terrifying is no one appears to have measured LNP accumulation in ovaries simulating the effect of multiple shots/boosters prior to declaring "safe & effective". They can't know because they never measured!

 

cc:

@Jikkyleaks

 

@KathMLee1

 

@DrJBhattacharya

 

@drcole12

Anonymous ID: 80be5e March 9, 2023, 8:07 a.m. No.18473874   🗄️.is 🔗kun   >>3913 >>3943 >>3983 >>4013 >>4278 >>4311

https://stacks.cdc.gov/view/cdc/26523/Email

https://archive.is/KY7UO

 

Use of Highly Pathogenic Avian Influenza A(H5N1) Gain-Of-Function Studies for Molecular-Based Surveillance and Pandemic Preparedness

 

December 12 2014

 

By Davis, C. Todd ; Chen, Li-Mei ; Pappas, Claudia ; …

Source: mBio. 2014; 5(6)

Anonymous ID: 80be5e March 9, 2023, 8:12 a.m. No.18473913   🗄️.is 🔗kun   >>3917 >>3943 >>3983 >>4013 >>4278 >>4311

>>18473874

Scientists seek ethics review of H5N1 gain-of-function research

Robert Roos March 29, 2013

 

Mar 29, 2013 (CIDRAP News) – A group of scientists acting under the aegis of a vaccine research advocacy organization has asked President Obama's bioethics committee to evaluate the ethics of experiments designed to increase the transmissibility of H5N1 avian influenza viruses.

 

The Foundation for Vaccine Research (FVR), a privately funded group that seeks to increase funding for vaccine research, argues that manipulating viruses to make them more deadly than they are in nature is "morally and ethically wrong," and that the ethical questions have been pushed aside in recent debate. Such experiments have been dubbed gain-of-function research.

 

The foundation made its request yesterday in a letter to Amy Gutmann, PhD, chair of the Presidential Commission for the Study of Bioethical Issues (PCSBI). The commission is a White House advisory committee that was set up in 2009. So far it has mostly addressed topics assigned to it by the president or federal agencies, but it can also address topics of interest to its own members, according to information on its Web site.

 

The FVR letter was signed by the group's chair, Simon Wain-Hobson, PhD; its executive director, Peter Hale, and 15 other scientists. The list includes such prominent names as Paul A. Offit, MD, of the Children's Hospital of Philadelphia; Marc Lipsitch, PhD, of the Harvard School of Public Health; Sir Richard Roberts, PhD, of New England Biolabs, a 1993 Nobel laureate; and Michael J. Imperiale, PhD, of the University of Michigan, a member of the National Science Advisory Board for Biosecurity (NSABB).

 

Wain-Hobson authored a Nature commentary this week that called for a halt to research designed to make viruses more transmissible, pending a thorough public discussion and independent risk assessment. The stated aim of such research on H5N1 is to identify which mutations might render the virus capable of spreading readily among humans, so that scientists could tell if the natural virus is starting to evolve in a dangerous direction.

 

Controversy over H5N1 research erupted in late 2011 when two groups of flu researchers revealed plans to publish studies involving lab-modified H5N1 viruses that could spread by air among ferrets. The NSABB objected to publishing the full details of the studies, but after a series of discussions, clarifications, and revisions, the two papers were published in May and June 2012. The studies were led by Ron Fouchier, PhD, of Erasmus Medical Center in the Netherlands, and Yoshihiro Kawaoka, DVM, of the University of Wisconsin.

 

Amid the controversy, a group of 40 prominent flu researchers announced a moratorium in January 2012 on further H5N1 gain-of-function research. The group called off the moratorium on Jan 23 of this year, saying the pause had allowed time for scientists to explain the potential benefits of the research and for governments and others to review relevant policies.

 

A spokeswoman for the PCSBI, Hillary Wicai Viers, acknowledged that the commission received the FVR's request but declined to comment on it further.

 

"Dr. Amy Gutmann, Chair of the Presidential Commission for the Study of Bioethical Issues, received the letter from the Foundation for Vaccine Research late Thursday afternoon," Viers told CIDRAP News via e-mail. "The Commission has not yet seen the letter though it looks forward to the opportunity to review the opinions of these distinguished scientists."

 

The letter calls on the commission to "consider the ethical issues raised by H5N1 gain-of-function research, especially experiments to increase the transmissibility of H5N1 viruses so they can be transmitted between humans as easily as the seasonal flu." H5N1 has a fatality rate of about 60% in confirmed cases, but it does not spread readily from person to person.

 

The accidental release of a lab-generated, human-transmissible H5N1 virus could "cause a global pandemic of epic proportions that would dwarf the 1918 Spanish flu pandemic that killed over 50 million people," the FVR letter says.

 

The foundation canvassed "a cross-section of life scientists" and found that most of them believed that manipulating a virus in the lab to make it more lethal is morally and ethically wrong.

 

Hale said the group has talked with close to 200 scientists, most of them virologists, about the issue since February 2012. "A large majority of them share all of these concerns, excluding the influenza people," he told CIDRAP News.

 

p1

Anonymous ID: 80be5e March 9, 2023, 8:12 a.m. No.18473917   🗄️.is 🔗kun   >>3943

>>18473913

The letter says that more gain-of-function studies on H5N1 and other viruses are on the way. A Chinese group is working with H5N1, and a Dutch group is expanding its H5N1 studies to include work with the H7N7 avian flu virus and has plans for similar research with the SARS coronavirus. Also, German scientists recently did experiments to see what it would take for canine distemper virus to spread from dogs to humans, the letter states.

 

Echoing concerns explained in the letter, Hale said, "It's become apparent over the past 15 months that the whole ethics issue has been brushed under the carpet. The talks on ethics have been on the margin."

 

He said the FVR thought White House officials or the Department of Health and Human Services (HHS) would ask the PCSBI to examine the ethics of the research, "but nobody did, and there was a vacuum there. That's why we did it."

 

The foundation feels that it's both appropriate and necessary for the commission to review the issue, given that the US government has funded most gain-of-function studies so far, the FVR letter says.

 

Hale said the steps taken by the federal government so far don't fully address the ethics of gain-of-function research. Among those steps, in February the National Institutes of Health announced a framework to guide decisions on funding for research designed to create H5N1 viruses capable of respiratory transmission in mammals. At the same time, the White House Office of Science and Technology Policy released a draft policy requiring federal agencies to routinely review the risks of funded studies involving 15 high-risk pathogens.

 

Hale said the FVR has reason to think the commission may be receptive to the request.

 

"We wouldn't have proceeded unless we knew in advance there was an excellent chance the commission would take up this issue," he said. "We can't think of an ethical issue that's more deserving to be looked at."

 

He said the foundation understands that most requests to the commission come from the White House or HHS, but one petition came from the National Biodefense Science Board.

 

According to information on the PCSBI Web site, the group is assigned topics by the president and federal departments, but it also can "choose a topic to study based on issues of interest to the members."

 

The commission has issued five reports so far. The most recent one, issued Mar 19, deals with the question of anthrax vaccine trials in children.

 

The FVR wants to see an independent risk assessment of gain-of-function research, Hale said. "It really is astonishing that 12 to 15 months into this debate we still don't have an indepenpent risk assessment." He added that the Government Accountability Office has been getting calls from lawmakers seeking such an assessment.

The FVR is primarily funded privately by its own board members, but it has received support from foundations, such as the Bill and Melinda Gates Foundation, for specific events, according to Hale.

 

See also:

 

Mar 27 CIDRAP News item about Nature commentary by the chair of the FVR

http://www.cidrap.umn.edu/cidrap/content/influenza/avianflu/news/mar2713scan.html

 

Feb 21 CIDRAP News story about federal policies on dual-use H5N1 research

http://www.cidrap.umn.edu/cidrap/content/influenza/avianflu/news/feb2113framework.html

 

Jan 23 CIDRAP News story about end of research moratorium

http://www.cidrap.umn.edu/cidrap/content/influenza/avianflu/news/jan2313moratorium.html

 

PCSBI site

http://bioethics.gov/

 

https://archive.is/sGtKI

Anonymous ID: 80be5e March 9, 2023, 8:14 a.m. No.18473924   🗄️.is 🔗kun

https://pubmed.ncbi.nlm.nih.gov/36160443/

 

Psychotropic drugs interaction with the lipid nanoparticle of COVID-19 mRNA therapeutics

 

Abstract

The messenger RNA (mRNA) vaccines for COVID-19, Pfizer-BioNTech and Moderna, were authorized in the US on an emergency basis in December of 2020. The rapid distribution of these therapeutics around the country and the world led to millions of people being vaccinated in a short time span, an action that decreased hospitalization and death but also heightened the concerns about adverse effects and drug-vaccine interactions. The COVID-19 mRNA vaccines are of particular interest as they form the vanguard of a range of other mRNA therapeutics that are currently in the development pipeline, focusing both on infectious diseases as well as oncological applications. The Vaccine Adverse Event Reporting System (VAERS) has gained additional attention during the COVID-19 pandemic, specifically regarding the rollout of mRNA therapeutics. However, for VAERS, absence of a reporting platform for drug-vaccine interactions left these events poorly defined. For example, chemotherapy, anticonvulsants, and antimalarials were documented to interfere with the mRNA vaccines, but much less is known about the other drugs that could interact with these therapeutics, causing adverse events or decreased efficacy. In addition, SARS-CoV-2 exploitation of host cytochrome P450 enzymes, reported in COVID-19 critical illness, highlights viral interference with drug metabolism. For example, patients with severe psychiatric illness (SPI) in treatment with clozapine often displayed elevated drug levels, emphasizing drug-vaccine interaction.

Anonymous ID: 80be5e March 9, 2023, 8:21 a.m. No.18473971   🗄️.is 🔗kun   >>4013 >>4278 >>4311

2013 H5N1 GAIN OF FUNCTION research

 

2013 same year DARPA contracted Moderna and Pfizer to create MRNA technologies

 

2023 MRNA technologies being introduced as best vaccine candidate for H5N1 potential 'PANdemic'…

 

Can you see it?