Dietary fat increases vitamin D-3 absorption
Bess Dawson-Hughes, Susan S Harris, Alice H Lichtenstein, Gregory Dolnikowski, Nancy J Palermo, Helen Rasmussen
PMID: 25441954 DOI: 10.1016/j.jand.2014.09.014
Abstract
Background: The plasma 25-hydroxyvitamin D response to supplementation with vitamin D varies widely, but vitamin D absorption differences based on diet composition is poorly understood.
Objectives: We tested the hypotheses that absorption of vitamin D-3 is greater when the supplement is taken with a meal containing fat than with a fat-free meal and that absorption is greater when the fat in the meal has a higher monounsaturated-to-polyunsaturated fatty acid ratio (MUFA:PUFA).
Design: Open, three-group, single-dose vitamin D-3 comparative absorption experiment.
Participants/setting: Our 1-day study was conducted in 50 healthy older men and women who were randomly assigned to one of three meal groups: fat-free meal, and a meal with 30% of calories as fat with a low (1:4) and one with a high (4:1) MUFA:PUFA. After a 12-hour fast, all subjects took a single 50,000 IU vitamin D-3 supplement with their test breakfast meal.
Main outcome measures: Plasma vitamin D-3 was measured by liquid chromatography-mass spectrometry before and 10, 12 (the expected peak), and 14 hours after the dose.
Statistical analyses performed: Means were compared with two-tailed t tests for independent samples. Group differences in vitamin D-3 absorption across the measurement time points were examined by analysis of variance with the repeated measures subcommand of the general linear models procedure.
Results: The mean peak (12-hour) plasma vitamin D-3 level after the dose was 32% (95% CI 11% to 52%) greater in subjects consuming fat-containing compared with fat-free meals (P=0.003). Absorption did not differ significantly at any time point in the high and low MUFA and PUFA groups.
Conclusions: The presence of fat in a meal with which a vitamin D-3 supplement is taken significantly enhances absorption of the supplement, but the MUFA:PUFA of the fat in that meal does not influence its absorption.
https://pubmed.ncbi.nlm.nih.gov/25441954/
Moar Pollshit
The data are based on aggregated polling data from 2022 Gallup telephone surveys, encompassing interviews with over 10,000 U.S. adults. In each survey, Gallup asks respondents if they identify as lesbian, gay, bisexual, transgender or something else, allowing them to choose multiple identities.
https://news.gallup.com/poll/470708/lgbt-identification-steady.aspx
President Donald J. Trump, 45th President of the United States of America, will deliver remarks in Manchester, New Hampshire on Thursday, April 27, 2023, at 4:00 PM EST.
Epstein was born on January 20, 1953, in Brooklyn, New York. His mother, Pauline, worked part-time as a school aide, and his father, Seymour, was a groundskeeper for the New York City Department of Parks and Recreation. Epstein, along with his younger brother Mark, were raised in a middle-class environment.
Review "The Protocols…" Fake or not….
Are they being enacted??
Anon should have been clearer, it was a suggestion, the question, rhetorical - anon knows the answer.
Photobomb, kek
>Rally Bread is Best Bread
Q Card
Crooked Joe Biden
The New Hampshire state legislators who endorsed him.