Cannabis hypermesis is about the only negative outcome associated with cannabis use. While you won't really read about it anywhere, it is linked to the terpene limonene…
Limonene will cause a spike in serotonin which is what causes nausea and stomach upset. Too much serotonin will cause the same symptoms.
In Canada they irradiate marijauna before it is sold. They do this as a pesticide (like cutting butter with a chain saw…). Given the idiocy of the act, it does result in killing all the terpenes BUT b-caryophyllene (which is heavy). And guess what? The Canadians do not have a CHS issue…
https://www.ncbi.nlm.nih.gov/books/NBK549915/