27 Jun, 2023 19:14
Janitor wipes out 20 years of ‘groundbreaking’ research
A laboratory freezer had been emitting an “annoying” beeping sound so the cleaner switched it off
A cleaner unwittingly destroyed over 20 years of “groundbreaking” research by switching off a laboratory freezer in a US university that had been emitting an “annoying” alarm sound, it has been claimed in a lawsuit.
The legal filing says that the janitor, who is not being sued in the lawsuit, tried to stop the repetitive beeping noise by switching off the freezer while working at the site in 2020. It is claiming damages in excess of $1 million from the cleaner’s employer, Daigle Cleaning Systems Inc., whom the Rensselaer Polytechnic Institute in upstate New York says failed to adequately train the contractor.
“[The] defendant, by and through its negligent, careless, and/or reckless supervision and control of [the janitor], caused damage to certain cell structures, samples, and/or research in the Lab,” the university claims.
The suit also states that sensitive samples contained in the freezer were required to be kept at precise temperatures, and that an alarm had begun to sound to notify staff of a small fluctuation. Scientists determined that the minute change in temperature was not enough to affect the samples.
https://www.rt.com/news/578813-us-lawsuit-freezer-alarm-janitor/
Maybe its a good thing that this happened, see what they research, they were growing cells for 20 years, maybe around the time all scientist were messing with RNA. It’s also a Private Institute. They study much more than samples below:
June 22, 2023
Rensselaer Researcher Uses Pressure To Understand RNA Dynamics
High pressure induces excited states, suggests role in HIV infection
Just as space holds infinite mysteries, when we zoom in at the level of biomolecules (one trillion times smaller than a meter), there is still so much to learn.
Rensselaer Polytechnic Institute’s Catherine Royer, Constellation Chair Professor of Bioinformatics and Biocomputation at the Shirley Ann Jackson, Ph.D. Center for Biotechnology and Interdisciplinary Studies(CBIS) and professor of biological sciences, is dedicated to understanding the conformational landscapes of biomolecules and how they modulate cell function. When biomolecules receive certain inputs, it can cause the atoms to rearrange and the biomolecule to change shape. This change in shape affects their function in cells, so understanding conformational dynamics is critical for drug development.
In research recently published in the Proceedings of the National Academy of Sciences, Royer and her team examined the conformational dynamics of a human transfer ribonucleic acid (tRNA) under high hydrostatic pressure. The high pressure led to an increased population of the tRNA-excited states that normally exist at very low levels, allowing new insights into tRNA function.
“We’re interested in observing the excited states because they lead to conformations outside of those that can be determined by X-ray crystallography, nuclear magnetic resonance (NMR), or electron microscopy,” said Royer. “We’re beginning to understand that there are far more biomolecular structures than previously thought and, for the development of therapeutics, we need to understand what these states look like.”
For this research, Royer used human tRNA rather than proteins, which are what she typically studies. “
May 23, 2023
RPI and Albany Medical College Researchers Awarded $3.3 Million To Improve Breast Cancer Treatment Using Artificial Intelligence
This latest project propels forward a longtime collaboration between Rensselaer Polytechnic Institute and Albany Medical College
Researchers from Rensselaer Polytechnic Institute (RPI) and Albany Medical College were awarded a $3.3 million grant over five years by the National Cancer Institute to use artificial intelligence (AI) to improve targeted drug therapy in HER2-positive breast cancer treatment. HER2-positive breast cancer tends to grow and spread quickly, but targeted treatments improve outcomes.
The research is being led by Xavier Intes, Rensselaer professor of biomedical engineering and co-director of the Center for Modeling, Simulation and Imaging in Medicine, and Margarida Barroso, a professor of molecular and cellular physiology and director of the Imaging Core Facility at Albany Medical College. RPI and Albany Medical College have collaborated continuously for over a decade focusing on treatments to improve human health supported by six major grants totaling over $15 million.This grant propels that collaboration forward using modern AI tools.
https://research.rpi.edu/about/signature-research-thrusts/biotechnology-and-life-sciences
https://news.rpi.edu/content/2023/06/22/rensselaer-researcher-uses-pressure-understand-rna-dynamics