https://www.msn.com/en-us/health/medical/mystery-of-elephant-testicles-could-hold-key-to-fountain-of-youth/ar-AA1dajE6?ocid

Metro

Mystery of elephant testicles could hold key to fountain of youth

Story by Katherine Fidler • 6h ago

Elephants have long intrigued scientists for the fact they rarely get cancer – and a new study suggests this may be linked to their testicles.

Unlike humans and most other land mammals, elephants’ testicles don’t descend outside the body. Instead, they remain high up inside, close to the kidneys.

Keeping the testicles cool is essential for good fertility – high temperatures can damage the sperm – suggesting significant adaptation in elephants given their core temperature has been recorded at upwards of 40C in the African savannah.

In addition to being very hot, elephants are also very big, which should increase their risk of cancer.

Body cells are constantly dividing, and with every division, there’s a risk of mutation that could lead to cancer. The more cells, as in larger animals, the greater the risk.

To combat mutations, the body has a specific gene, TP53, which produces the protein p53. The main role of p53 is to identify and ‘neutralise’ damaged DNA during cell division, helping combat the spread of mutations and earning it the nickname ‘Guardian of the Genome’.

Humans only have one copy of the gene. Elephants have 20.

Scientists now believe they may have developed this super-charged defence against cancer as a byproduct of their ‘hot testicles’.

‘Guardian of the Genome’.

https://www.dailymail.co.uk/news/article-12246843/Daycare-worker-accused-sending-nude-photos-children-trans-New-Hampshire-Democrat-court.html

Chaos erupts as daycare worker accused of sending nude photos of children to trans New Hampshire Democrat appears in court: 'You need to rot in hell!'

Lindsay Groves, 38, is accused of taking nude photos of children aged 3 to 4

She had her first hearing Wednesday at Moakley Federal Courthouse in Boston

A mother started yelling at her at the end of the hearing and was escorted out

Chaos erupted at a Massachusetts courtroom during the first court appearance of a daycare worker accused of sending photos of naked children to a trans former politician.

Lindsay Groves, 38, appeared in court on Wednesday to face accusations that she took nude images of children aged three to five at the Creative Minds Early Learning Center in Tyngsboro, about 35 miles northwest of Boston.

Prosecutors say the New Hampshire resident took the photos in a private bathroom during breaks before nap time and texted them to someone 'with whom she was previously in an intimate relationship' and shared 2,500 texts with.

The investigation into Groves also led to the arrest of Stacie Laughton, 39, who is believed to be the first transgender person elected to a state Legislature in the nation. She is charged with distributing child pornography.

Several parents were present during Groves' first court appearance at Moakley Federal Courthouse in Boston, with one of them yelling at her as she was being lead away from the courtroom at the end of the hearing.

'I want to f** kill that b**,' said an unidentified tearful mother from the gallery, as reported by the Boston Herald.

'You need to rot in jail!'

The mother was then escorted out by a U.S. Marshal and the people she was with, who tried to calm her down, per local reports.

Another mother present at the hearing, Rosemary Denomme, spoke to NBC10 outside the courtroom, saying 'We just all hope that she is just taken down.'

Denomme said her four-year-old daughter attended the day care and still doesn't know if her child is one of the victims.

'As any parent would, you want to grab her, but you don't want to get kicked out,' she said of how she felt during the hearing.

'I came down like any parent would, you want to follow this and I want to fight the fight for my daughter and all those kids.'

Laughton was elected in 2012, but was unable to serve after her criminal past emerged in which she was sentenced to probation stemming from a 2008 felony conviction for credit card fraud.

Nashua Police Department began an investigation into the allegations after receiving a tip off.

According to the affidavit, Groves 'allegedly used natural bathroom breaks for the children,' such as 'routine diaper pull-up changes prior to naptime … to take multiple photos of the prepubescent children in a private bathroom and then sent the photos to the (former intimate partner) via text message' with an alleged 2,500 texts.

The texts allegedly included discussion of the explicit images and their transfer. They also included at least four sexually explicit images of children between the ages of three to five, per police.