Anonymous ID: 86434c Nov. 21, 2023, 5:44 a.m. No.19952740   🗄️.is đź”—kun   >>2750 >>2873 >>2911 >>2916 >>2932 >>2945 >>3046

ticks are the vector for 'zombies', it appears

 

https://www.msn.com/en-us/health/other/yellowstone-national-park-confirms-first-case-of-zombie-deer-disease/ar-AA1keUZe

 

'Zombie Deer Disease' Confirmed at Yellowstone

A rare and fatal illness, chronic wasting disease (CWD), colloquially known as "zombie deer disease," has been detected in Yellowstone National Park for the first time, sparking concerns among wildlife experts and conservationists.

 

After running multiple diagnostic tests, the National Park Service confirmed the presence of the disease in an adult mule deer found near Yellowstone Lake. The deer was part of a population study by Wyoming's Game and Fish Department and had been fitted with a GPS collar.

 

"CWD is a contagious, fatal disease of deer, elk and moose caused by a malformed protein [prion] for which there is no vaccine or known treatment," the National Park Service wrote in a statement.

 

The malformed protein builds up in the brain and other tissues causing psychological and behavioral changes, like excessive drooling, listlessness, weight loss and eventual death. The disease, which impacts the central nervous system, can take more than a year to manifest visible symptoms in animals.

 

The disease has been found in animal populations in at least 31 U.S. states, Canada, Norway, Finland, Sweden and South Korea, according to the U.S. Centers for Disease Control and Prevention (CDC).

 

There have been no reported cases of infection in humans, however, "because of the long time it takes before any symptoms of disease appear, scientists expect the [CWD transmission] study to take many years before they will determine what the risk, if any, of CWD is to people," the CDC said.

 

The CDC recommends that hunters remain cautious and test the deer or elk meat for CDW before consuming.

The contagious disease is transmitted via bodily fluids and waste, including saliva, urine, feces, and contaminated soil.

 

"Experts believe CWD prions can remain in the environment for a long time, so other animals can contract CWD from the environment even after an infected deer or elk has died," the CDC said.

 

Once established in an area, "there is currently no effective strategy to eradicate it," the National Park Service said. Therefore, the disease poses a significant challenge to wildlife management.

 

The National Park Service is working with other agencies to identify at-risk areas and is increasing monitoring and sample testing. Yellowstone is updating its surveillance plan, as well. In the meantime, the park has warned visitors to stay away from wildlife.

 

https://vet.ucalgary.ca/news/chronic-wasting-disease-may-transmit-humans-research-finds

 

Chronic wasting disease may transmit to humans, research finds

Chronic wasting disease (CWD), a highly infectious and fatal neurological disease that’s spreading through North American herds of elk, moose, mule and white-tailed deer, may be more transmissible to humans than previously thought. Researchers in the University of Calgary Faculty of Veterinary Medicine (UCVM) have published a paper in Acta Neuropathologica that shows there is a risk of zoonotic transmission of the prion disease.

“This is the first study to show that the barrier for CWD prions to infect humans is not absolute and that there is an actual risk that it can transmit to humans,” says Dr. Sabine Gilch, PhD, associate professor and Canada Research Chair in Prion Disease Research at UCVM. Prion diseases attack proteins in the brain, causing clumps to form and eventually, death.

 

Two well-known prion diseases are bovine spongiform encephalopathy (BSE), or Mad Cow Disease, in cattle and Creutzfeldt-Jakob disease in humans. “From Mad Cow Disease we know that prion diseases can jump the transmission barrier from animals to humans,” says Gilch. “During the BSE crisis, BSE was transmitted through contaminated meat or food products to humans and caused a new form of human prion disease, called variant Creutzfeldt-Jakob disease.”

 

Previous research into CWD has studied hunters who consume game in geographies with high prevalence of the disease in animals and found no evidence of human infection. “This study is an experimental model, yet it gives a lot of new information and insight to the zoonotic potential of CWD if you compare it with other published studies,” says lead author Dr. Samia Hannaoui, PhD, research associate in the Gilch lab.

p1

Anonymous ID: 86434c Nov. 21, 2023, 5:47 a.m. No.19952750   🗄️.is đź”—kun

>>19952740

 

Hannaoui and her colleagues Irina Zemlyankina, Chris (Sheng Chun) Chang and Maria Arifin took CWD isolates from infected deer and injected them into “humanized” mouse models. Over a period of years, the mice developed CWD. Further, the mice were found to shed infectious prions in feces.

 

“The implication is that CWD in humans might be contagious and transmit from person to person,” says Gilch.

 

Samia Hannaoui

Another “compelling” finding by the researchers is that CWD may show up differently in humans than in animals and other human prion diseases, and be difficult to diagnose with current methods used to screen for human prion disease. “Biochemically, the signature of this transmission is different from the classical signature of other prion diseases,” says Hannaoui.

 

“When we look at humans, we usually see a typical signature. And in this mouse model we did not find that signature, which means if this ever happens with humans, it will not look like the prion diseases that we know. It might be significantly different from whatever we know so far.”

 

While the study provides evidence supporting the potential of animal to human transmission of CWD prions, Hannaoui cautions more research is required. “This does not mean that CWD is zoonotic. We're far away from that,” she says. “This study is really important to make people aware that CWD in humans might be completely different from what's expected and from other known prion diseases. And that it could have the potential to transmit from human to human.”

 

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