>>20360126
Need to smoke a menthol cigarette after eating the Flaming Hots.
Menthol's ability to chemically trigger the cold-sensitive TRPM8 receptors in the skin is responsible for the well-known cooling sensation it provokes when inhaled, eaten, or applied to the skin.[3] In this sense, it is similar to capsaicin, the chemical responsible for the spiciness of hot chilis (which stimulates heat sensors, also without causing an actual change in temperature).
Menthol's analgesic properties are mediated through a selective activation of κ-opioid receptors.[4] Menthol blocks calcium channels[5] and voltage-sensitive sodium channels, reducing neural activity that may stimulate muscles.[6]
Some studies show that menthol acts as a GABAA receptor positive allosteric modulator and increases GABAergic transmission in PAG neurons.[7] Menthol has anesthetic properties similar to, though less potent than, propofol because it interacts with the same sites on the GABAA receptor.[8] Menthol may also enhance the activity of glycine receptors and negatively modulate 5-HT3 receptors and nAChRs.[
https://en.wikipedia.org/wiki/Menthol