Huge. Notable.
It seems to suggest, pending further investigation, that taking metformin may (MAY) increase your risk of developing Alzheimer's disease.
Most pharmaceuticals are at least relatively safe, in that their benefits outweigh their drawbacks.
I think the 99% referred to the proportion of people who would have to be hospitalized for shock if they knew everything Q, POTUS, etc knew.
Wrong. And I guarantee I know a lot more about it than you.