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1α-Hydroxyvitamin D5
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Vitamin D5
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From Wikipedia, the free encyclopedia
Not to be confused with decamethylcyclopentasiloxane.
Vitamin D5
Names
IUPAC name
(1S,3Z)-3-[(2E)-2-[(1R,3aS,7aR)-1-[(1R,4S)-4-ethyl-1,5-dimethylhexyl]-7a-methyl-2,3,3a,5,6,7-hexahydro-1H-inden-4-ylidene]ethylidene]-4-methylene-1-cyclohexanol
Other names
Sitocalciferol
(5Z,7E)-(3S)-9,10-secoporiferasta-5,7,10(19)-trien-3-ol
Identifiers
CAS Number
71761-06-3 check
3D model (JSmol)
Interactive image
ChEBI
CHEBI:33279
ChemSpider
7826639 check
PubChem CID
9547700
UNII
0W2I161LCL check
InChI
SMILES
Properties
Chemical formula
C29H48O
Molar mass 412.702 g·mol−1
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
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Infobox references
Vitamin D5 (sitocalciferol) is a form of vitamin D.
Research
Analogs of calcitriol, a form of vitamin D3, have been proposed for use as antitumor agents.[1][2][3] Studies on vitamin D3 have shown inhibition of cell proliferation in prostate cancer, but high doses of vitamin D3 result in hypercalcemia. The effects of vitamin D5 on prostate cancer have also been studied, and unlike vitamin D3, vitamin D5 does not cause hypercalcemia while inhibiting tumor cell proliferation.[4] The most researched analogue of vitamin D5 as an antitumor agent is 1α-hydroxyvitamin D5.
https://en.wikipedia.org/wiki/Vitamin_D5