After Cain slew Abel, GOD cast him out of the Garden of Eden and CAIN WENT EAST.
Jesus proclaimed Satan, "their father", to have been a murderer from the begining. (John 8:44)
Jesus was addressing the Pharasees.
They were the servents of Herod the Edomite.
Esau is Edom.
GOD hates Esau. (Malachi 1:2-3
Esau married Canaanites.
Jesus was killed by Edomite coverts to Judaism, who, through the Romans, took over control of Judea.