Massie has been outspoken against the American Israel Public Affairs Committee and its influence on American politics, and in December 2023 tweeted out a meme appearing to contrast Zionism with American patriotism.[102] In May 2024, AIPAC and allied groups announced a $300,000 ad campaign targeting Massie for perceived “anti-Israel views” while not officially endorsing any primary challenger.[103] Massie responded by posting a poll on X asking his followers whether AIPAC should be forced to register as a foreign agent.[104] In a June 2024 interview, he claimed that each Republican member of Congress besides himself has an "AIPAC person" that directs them to vote in line with the positions of the organization.[105]
In 2019, Massie was the only member of Congress to oppose an act that refused to recognize Russia's annexation of Crimea.[106] He was also one of three members to oppose a March 2022 resolution supporting Ukraine's sovereignty after it was invaded by Russia.[107][106] He later amplified Russian claims that Ukraine was developing biological weapons. Referring to Victoria Nuland's statement that Ukraine had biological research facilities that the U.S. feared might be seized by Russia, Massie tweeted, "I didn’t take the concern over Ukrainian biological labs seriously … until now."[108] Massie opposed a resolution in 2022 to support Sweden and Finland joining NATO, saying he did not want to "subsidize socialist Europe's defense".[109] In March 2024 he voted against House Resolution 149 condemning the illegal abduction and forcible transfer of children from Ukraine to the Russian Federation, one of nine Republicans to do so.[110]
Massie voted "present" on the 2015 Iran nuclear agreement, the only member of the House to do so and the only Republican not to vote against it.[111] Massie was the only member of the House to vote against extending sanctions on Iran in 2016.[112] He was also one of only three House members to vote against a 2017 bill to impose new sanctions on Iran, Russia, and North Korea.[113]
Massie is a part of a small group of Republicans who voted against a House resolution reaffirming commitment to the orderly and peaceful transfer of power in the United States under democratic principles.[181][182] He was also one of seven Republicans who did not support their colleagues' efforts to challenge the results of the 2020 presidential election on January 6, 2021; these seven signed a letter that, while giving credence to election fraud allegations made by President Donald Trump, said Congress did not have the authority to influence the election's outcome.[183]
Massie endorsed Florida Governor Ron DeSantis for president in the 2024 election, saying that "America needs a leader who is decisive, respects the Constitution, understands policy, puts family first, and leads by inspiring".[189]