Anonymous ID: 7e8279 Dec. 22, 2024, 3:49 p.m. No.22212396   🗄️.is 🔗kun

>>22212280

> Rather than protecting infants from RSV, these novel injections seem to have worsened the severity of infections

How the World’s First Dengue Vaccination Drive Ended in Disaster

Is a runaway immune reaction making a dengue vaccine dangerous?

 

Among Asian children two to five years old, those who had received the vaccine were seven times more likely than unvaccinated children to have been hospitalized for serious dengue in the third year after vaccination.

 

… the vaccine was acting like a first dengue infection, priming the body with just the right quantity of Trojan-horse antibodies to help a real infection turn severe.

 

In July 2018 Sanofi Pasteur published its reanalysis of clinical trial data using the Pittsburgh test in the New England Journal of Medicine. The review confirmed a higher risk of severe disease and hospitalization in “seronegative” children (those who had no evidence of prior dengue infection in their blood) who had received the vaccine, compared with those who had not. The “vaccine partially mimics primary infection and increases the risk of severe dengue during subsequent infection,”