2025 CNBC Disruptor 50: See the full list of companies leading new era of AI breakthroughs and richesTue, Jun 10 2025 AM EDT CNBC.com staff@CNBC
The race for global supremacy in AI and the existential threat it represents to the status quo in the tech industry, and beyond,has led to record venture investment in startups.
The top five companies on this year’s Disruptor 50 list —including a new No. 1 Disruptor from the defense tech sector— have a combined valuation of just under $500 billion. That is more than the combined total valuation of almost every past Disruptor 50 list over the last 12 years.
One recently hauled in the largest VC round ever, and as consumer and business use of artificial intelligence rapidly grows, more are using their cash to become aggressive acquirers, as they exponentially scale their generative AI business models.
But it’s never just about the money or size in the Disruptor 50 selection process, and it is far from all agentic AI and chatbots, with new business models emerging in a wide range of areas, from agriculture to autonomous transportation and health care.
It is increasingly about the new gen AI era, which began transforming the Disruptor 50 list in 2023, and hasn’t slowed down since. Twenty of this year’s 50 companies have made the list for the first time, while another 19 were first-timers in either 2023 or 2024. For most, embracing the new era is what has kept them here.
In all, the 2025 Disruptors have raised $127 billion at a total implied valuation $798 billion.
1 Anduril Leading a new military-technological complex
2 OpenAI Record users, record cash
3 Databricks Building blocks of intelligence
4 Anthropic The big business case for AI
5 Canva Creative visualization
6 Ramp Freeing up more finance
7 Flock Safety A crime fighter
8 AlphaSense Market intelligence
9 Octopus Energy The new power generation
10 Stripe Processing-oriented
11 Revolut British banker
12 Thrive Market A healthier shopping habit
13 Metropolis The spot to be in parking
14 Transcarent They care
15 Lead Bank Fintech’s fixer
16 Carbon Robotics Weedtech
17 Virta Health What comes after GLP-1s
18 Fruitist The berry unicorn
19 Saronic Technologies In the autonomous navy
20 GrubMarket Food’s supply side
21 MoonPay Moving with crypto wherever it goes
22 Writer A model worker
23 ŌURA Put a ring on it
24 Einride Self-driving semis
25 Abnormal AI Phishy business
26 Iambic Therapeutics Small molecules, big drug discoveries
27 Perplexity Search and deploy
28 Scale AI AGI’s data foundry
29 Rippling Employee management reset
30 Gecko Robotics Before things break
31 Footprint Putting things in a new package
32 Harvey Lawyering up AI
33 Apptronik 5 feet 8 inches, 160 lbs, all robot
34 Notion Lego my work
35 Waabi How self-driving trucks see and learn
36 Zum A better ride to school
37 Formation Bio A lifeline for stalled drugs
38 Shield AI Drone force
39 Navan Business travel’s super app
40 VAST Data The gen AI stack
41 Rad AI Radiology’s new set of eyes
42 Glean Enterprising search
43 ElevateBio Domestic biotech manufacturing
44 Exotec The robot warehouse rise
45 Figma The redesigner
46 Zipline Frequent drone flyer
47 Abridge Getting a doctor’s note
48 Sierra Chatting you up
49 Esusu Treating renters like owners
50 Runway Lights, camera, gen AI
https://www.cnbc.com/2025/06/10/2025-cnbc-disruptor-50-see-the-full-list-of-companies.html