Acetaminophen decreases intracellular glutathione levels
If glutathione levels are zapped or incapacitated it appears to open the door to all kinds of things. It's supposed to help " Transportation of mercury out of cells and the brain." I assume it transports more than mercury. Glutathione appears to have been a target. But there are several attacks going on to supplement the effects including fluoride. Deficiency of glutathione can lead to leaky gut which causes inflammation and inflammation also affects the brain. Low levels seem to be also involved in insulin resistance, type 2 diabetes, Alzheimer disease and may(?) contribute to cholesterol issues. Cholesterol is brain food.
Depletion of glutathione is the gift that keeps on giving- to big pharma and rich pockets. The increase in autism and disease has been in the works for some time. Give a kid a shot, give him Tylenol and fluoridate his water. Triple whammy.
I had to run through this quickly and hope others more adept and educated in the science than myself can continue on.
From an AI Overview:
Inhibiting glutathione levels increases oxidative stress, damages cells, and can play a role in the development of various diseases, including neurodegenerative disorders and cancer. Glutathione is the body's most powerful antioxidant. Inhibiting glutathione leads to
impaired detoxification, disruption of immune function, promotion of disease development and progression.
https://pmc.ncbi.nlm.nih.gov/articles/PMC4684116
Critical Role of Glutathione in Detoxification, Inflammation, and So Much More
"It is hard to overstate the importance of glutathione, key roles of which are summarized in Table 1. It plays a crucial role in shielding cellular macromolecules from endogenous and exogenous reactive oxygen and nitrogen species. While it directly quenches some free radicals, of perhaps greater importance is that it deals directly with the causes of oxidative stress such as mercury and POPs."( Persistent organic pollutants)
From an AI Overview:
Yes, FLUORIDE affects glutathione, typically decreasing and depleting it by inducing oxidative stress and inhibiting the enzymes responsible for its production.
https://pmc.ncbi.nim.nih.gov/articles/PMC7175316
https://www.sciencedirect.com/science/article/pii/S0013935121010112
AI Overview
Yes, studies show that fluoride can affect cholesterol levels though effects can vary based on diet and species.
https://pubmed.ncbi.nim.nih.gov/25461561/
https://pmc.ncbi.nim.nih.gov/articles/PMC6904509