Over 1,100 Studies Expose 12 Natural Compounds with Serious Anti-Cancer Power
Cancer is exploding worldwide… but the safest natural compounds are still ignored. Almost like the silence is profitable.
Nov 26, 2025
THE 12 NATURAL ANTI-CANCER COMPOUNDS
-
Apigenin (Chamomile)
Helps immune cells detect tumors (reduces PD-L1)
Slows growth signals inside cancer cells (inhibits PI3K/AKT, EGFR, ERK)
Improves chemotherapy responsiveness (reduces MDR1/P-gp activity)
Limits tissue invasion (suppresses NF-κB, MMP-2/9)
Induces cell death through several pathways (apoptosis, autophagy, ferroptosis)
-
Artemisinin (Sweet Wormwood)
Generates oxidative stress inside tumors (ROS, lipid peroxidation)
Restricts blood vessel formation (anti-angiogenic)
Slows cancer cell movement (reduces vimentin, N-cadherin)
Helps counter drug resistance (affects STAT3, AKT, HSP90)
Shows activity across many animal tumor models
-
Berberine (Coptis / Goldenseal)
Disrupts major growth pathways (PI3K/AKT, HER2, TGF-β)
Reduces tumor-fueling inflammation (NF-κB)
Helps reverse drug resistance (P-gp, MRP1, NRF2)
Lowers immune evasion signals (PD-L1)
Reduces metastatic behavior (MMP-2/9)
-
Curcumin (Turmeric)
Triggers cancer cell death (apoptosis, autophagy, ferroptosis)
Lowers inflammation inside tumors (NF-κB, STAT3)
Blocks blood vessel growth (VEGF inhibition)
Helps reverse chemotherapy resistance (P-gp, BCRP)
Reduces invasive behavior (Twist1, MMP-9, EMT markers)
-
Emodin (Rhubarb Root / Japanese Knotweed)
Interferes with cancer cell communication (Wnt/β-catenin, STAT3, NF-κB)
Initiates several types of cell death (necroptosis, ferroptosis)
Disrupts cancer metabolism (GLUT1 reduction)
Limits spread by reducing enzymes that break tissue barriers (MMP-2/9)
Helps counter drug resistance (P-gp, GST)
-
EGCG (Green Tea)
Slows growth by interrupting major pathways (PI3K/AKT/mTOR)
Promotes programmed cell death (Bax↑, Bcl-2↓)
Reduces inflammation (STAT3)
Inhibits invasion and angiogenesis (MMP-2/9, VEGF)
Decreases drug resistance (P-gp suppression)
-
Ginsenosides (Ginseng)
Reduce metastatic behavior (EMT inhibition, MMP suppression)
Improve immune responses (STAT3 downregulation)
Promote cancer cell death (caspase activation)
Help restore normal growth regulation (p53, PTEN)
Some forms influence gut microbiota related to tumor microenvironments
more:
https://www.vigilantfox.com/p/over-1100-studies-expose-12-natural