Fungal Persistence of SARS-CoV-2 Spike Protein from Residual Plasmid DNA: A Non-Viral Pandemic Model

The COVID-19 pandemic, conventionally attributed to zoonotic transmission of a replicating SARS-CoV-2 virus, exhibits clinical heterogeneity that challenges a singular infectious paradigm. This manuscript synthesizes evidence from exclusively open-access, peer-reviewed literature to propose an alternative model: aerosolized or fomite-disseminated plasmid DNA encoding the SARS-CoV-2 spike (S) glycoprotein—derived from biopharmaceutical production pipelines—serves as the initiating agent. Commensal fungi (e.g., Candida albicans, Malassezia restricta, Saccharomyces boulardii) in human mucosal biofilms acquire this plasmid via endocytosis and integrate it chromosomally through non-homologous end-joining, leading to constitutive S-protein expression and secretion via extracellular vesicles (EVs).

https://x.com/drtaubraun/status/1997230673367642352