Anomalous intravascular casts with firm, rubber-elastic properties have been increasingly noted by embalmers and clinicians since 2021. To establish their structural characteristics, we performed blinded morphological and histological evaluations. Gross examination revealed elongated, lumen-filling casts up to 25 cm in length, frequently branching and demonstrating elastic resistance atypical of conventional thrombi. Histology demonstrated dense fibrinous lamination with intermittent Lines of Zahn and various cellular inclusions content, suggesting antemortem formation under atypical hemodynamic conditions. These structural features differ from both physiological thrombi and postmortem clots, indicating a distinct pathological phenotype. Further biochemical and molecular analyses will be required to determine the composition and mechanisms underlying these structures.

https://www.preprints.org/manuscript/202601.1846/v1

In the first paper of this trilogy, anomalous intravascular casts (AICs) were established as a discrete morphological–histological phenotype distinct from conventional antemortem thrombi and ordinary postmortem clots. While those findings demonstrated that AICs form coherent, lumen-conforming intravascular structures under conditions of active blood flow, morphology and histology alone cannot determine the biochemical nature of the matrix from which such structures are formed.Blinded, multi-site elemental analyses were performed on anomalous intravascular casts using inductively coupled plasma mass spectrometry (ICP-MS). Elemental compositions were benchmarked against whole-blood reference values and first-principles stoichiometric expectations derived from fibrinogen to assess compatibility with canonical fibrin-based clot biochemistry.AICs exhibited reproducible, non-physiological elemental ratios characterized by marked sulfur depletion, relative phosphorus enrichment, and imbalance within bulk elemental relationships. These compositional features are incompatible with protein-dominant fibrin matrices and could not be explained by simple fibrin overload, cellular aggregation, or classical coagulation artifacts.The elemental composition of anomalous intravascular casts is inconsistent with canonical thrombus biochemistry and supports the presence of a non-canonical intravascular matrix. These findings independently corroborate the structural conclusions of the first paper in this series and establish the need for protein-level analysis to identify the molecular constituents underlying this anomalous material, which is addressed in the final paper of this trilogy.

https://www.preprints.org/manuscript/202601.2149/v1

Since early 2021, anomalous intravascular casts (AICs) have been reported that differ markedly from conventional thrombi in morphology, persistence, and mechanical behavior. Prior histological and elemental analyses suggested an atypical clot matrix.We performed blinded proteomic profiling of AIC specimens using HPLC-MS/MS (High Precision Liquid Chromatography - tandem Mass Spectrometry) to characterize their protein composition and assess markers of fibrin architecture and fibrinolytic capacity.Proteomic analysis identified 541 human proteins, dominated by fibrin-family components. However, fibrinogen chains were present in highly abnormal proportions, with pronounced depletion of the α chain relative to β and γ chains. Plasminogen was detected at extremely low abundance (0.1283% of total protein), indicating a severe deficiency in intrinsic fibrinolytic machinery.AICs exhibit a reproducible proteomic phenotype incompatible with typical fibrin biology, characterized by chain imbalance and fibrinolysis resistance. These findings support classification of AICs as structurally and functionally abnormal clot entities and motivate further mechanistic investigation.

https://www.preprints.org/manuscript/202601.2319/v1

>>24291053

Is his mouth writing checks that other peoples bodies have to cash?

>>24291050 need law: mandatory coroner forensic exam of sudden deaths to identify these white clots prevalence and role in death. Law for embalmers to report presence of white clots.

How many living people right now are carrying these white clots? Are they still growing?

What causes these white clots?

Maralago shooter with gas can kilt

Explosions in northern Iran

Russian plane activity

Protestors back on streets

Looks like regime change is back on the menu boys

>>24291397 seven different explosions in Paran, power outages

Explosion at missile base of revolutionary guard

IL-76 emergency ministry transports from Russia==Iran? ==> UAE who did they extract?

>>24291424 FAFO

Sad! Many such cases.

>>24291449

Native American Gator Hunter Runs out of Gas at Mar a Lago, Gunned Down by Rogue Feds