>there's bad jews and good jews
yeah?
well the good jews better step up to the plate
REAL FUCKING SOON
>thalidomide
some organic molecules have a 3D structure that is totally assymetric
which means that atoms connected in identical sequences
occur in "left-handed" and "right-handed" stereoisomers
stereoisomers are extremely difficult to separate
and likewise it is extremely difficult to synthesize only one of them at a time
thalidomide is one such organic chemical
when thalidomide was developed in a lab it was naturally in very small quatities
at that scale cost was not a major consideration
so it was prepared as a pure stereoisomer, not mixed with its "mirror-image" version
in that form, the tests showed the single stereoisomer was both effective and safe for use in humans
HOWEVER…
when production was scaled up to produce the ton quantities needed to distribute millions of prescriptions
the cost of separation and/or "stereo-selective" synthesis became financially prohibitive
experience with a great many other assymetric chemicals had shown that the "inactive" stereoisomer" is merely biologically "inert"
so they went ahead and began production of thalidomide that produced an equal mix of both left and right handed isomers
with the perfectly reasonable expectation that the inactive isomer would be inert "filler"
it was not
the horrific birth defects were entirely due to the presence of the mirror-image isomer of the safe and effective isomer
this played a significant part in the difficulty and delay in recognizing the Rx form of thalidomide as the causitive agent in the birth defects
MORAL…
sometimes it's CRITICAL for the left hand to know what the right hand is doing
>let Bill and Hillary Clinton testify virtually from the comfort of their Chappaqua home
sure…
provided that US marshalls are present to verify their identity with DNA testkits
otherwise there is plausible deniability
you know
the thing
>WWG1WGA!
>This dickhead is now calling himself a dr
original definition of a doctorate: an original contribution to basic research extending our understanding of the universe
nowadays, they award doctorates for…
athletic trainer
business administration
church music
design (?)
environment
forestry
hebrew studies
juristic science
library science
missiology
physical education
public administration
recreation
social work
to name but a few
>somehow this is antisemetic
are you jewish?
only "God's Chosen People"™ have the authority to decide what is and what isn't antisemitic
CONSIDERING JOINT REPLACEMENT SURGERY? - DON'T DO IT
Prosthetic Joint Infection (PJI): a growing, under-recognized crisis
Total joint replacement is now the most common major surgical procedure performed worldwide, with volumes accelerating as populations age and obesity, diabetes, and other chronic conditions rise1. While joint replacement outcomes are typically excellent, prosthetic joint infection (PJI) remains the most devastating complication, capable of turning a successful joint replacement into a patient’s and surgeon’s worst nightmare. At any time following surgery—months or even years later—patients can develop a PJI, a serious and potentially life-threatening condition. PJI patients frequently experience severe morbidity, prolonged immobility, loss of independence and productivity, and a five-year mortality rate approaching 25%2, rivaling many cancers. Despite this impact, there are no approved therapeutics in the U.S. specifically indicated for PJI, leaving patients with limited and often unsuccessful treatment options.
Biofilm is the common enemy—and the reason current treatments fail. Hardware-associated infections are uniquely difficult to eradicate because bacteria adhere to implant surfaces and surrounding tissues, forming difficult-to treat-biofilms. These biofilms can block antibiotic penetration and protect dormant bacteria that can persist, despite aggressive therapy. As a result, standard-of-care approaches frequently fail, forcing patients into cycles of repeated surgeries, loss of mobility, hospitalizations, and prolonged antibiotic exposure.
How Often PJI Occurs: PJI occurs in approximately 2.3% and 2.1% of total knee and total hip replacements respectively3, but the risk is two- to three-fold higher (3–5% or more) in patients with high-risk co-morbidities such as obesity, diabetes, renal disease, immune suppression, or prior joint surgery. In the U.S. alone, ~45,000 PJI cases occur each year, and this number is expected to grow substantially as procedure volumes increase. Importantly, PJI is widely underreported in registries and administrative datasets, particularly late-onset and recurrent infections, meaning the true burden is likely significantly higher than reported figures suggest. The problem is accelerating. By 2030, annual volume of knee and hip replacements across the U.S. and Europe is projected to be over 5 million4, each carrying a PJI risk that current medicine cannot reliably prevent or cure. As procedure volumes rise and patient risk profiles worsen, the absolute number of infections—and failures—will continue to climb.
The Burden of PJI: Current treatment pathways demand unacceptable trade-offs. Implant-preserving procedures such as DAIR (debridement, antibiotics, and implant retention) report failure rates of 35-55% in the published literature5. Two-stage revision—the most aggressive surgical option—requires multiple major operations, extended hospitalization, and months of disability, yet still fails 15–25% of the time. The economic impact mirrors the clinical burden: total costs for a single PJI episode often exceed $390,000 per patient, according to data published by Hany Bedair, MD in Clinical Orthopaedics and Related Research.
The implications extend far beyond individual patients. Healthcare systems face mounting pressure from longer hospital stays, repeat surgeries, antibiotic toxicity, and complex care coordination. PJI represents a large, growing, and underserved market—one where effective, biofilm-targeted therapies could fundamentally change outcomes while delivering meaningful value to patients, providers, and payers alike.
https://peptilogics.com/pipeline/#pji
it's SPELLED "fumunda" cheese, nigger
>a slang term for the, often pungent, buildup of sweat, dead skin, and bacteria that accumulates in the genital area
apparently it also fills your cranial cavity
and it's STILL SPELLED "fumunda"
fuckwit
>Fromunda my nuts you faggot
yeah…
and i guess you "DIDN'T DO NOTHING"
i know what it is
and i KNOW how it's pronounce and spelled
now go fuck your sister-wife agin, jeffro
>Nixon was the last honest man in politics in the USA
sry…
jimmy carter was the last honest, God-fearing president
>Jimmy the peanut was a crafted JFK-like Rockefeller Howdy Doody puppet product. He was batshit cray cray
how old were you when he was elected, CHILD?
>i was a cub scout in 1980
so when it comes to jimmy carter (or ronnie raygun), you admit you don't know your ass from a hole in the ground
>filtered for being an assuming homo
and yet you replied to my post
and i replied to your reply
who started the thread is irrelevant
your retardation speaks for itself
GFY
only fegele announce the filter
>Nixon was right.
nixon was Ike's VP
he knew about cia black ops
he knew who the S-team were
he recognized their handiwork in dallas
he was paranoid they were after him
he threatened to blow the lid off
they considered him a loose cannon
but they couldn't risk another assassination so soon after jfk
might make normies wonder WTF
so they used his paranoia against him
suckered him into implicating himself in political spying
then used the MSM for character assassination
and offered to let him live if he resigned
OR….
mebee the roads followed topological lines
for ease of construction / travel
and the aerial view is just coincidence
>flash your boobs Melanis
>Kissinger was not.