>>3434347
This sound like you?
Honestly, this looks like pharmagic to me. There really isn't even all that much solid evidence to conslusively demonstrate massive uptake in seratonin from SSRI's, and you would think this informational "case study" would list MDMA in clinical manifestations (because that's the REAL seratonin increase) but it doesn't. Not trying to take from your experience, anon... these just rarely pass test for me.
"SS presents with a classical triad comprised of mental status changes, autonomic hyperactivity and neuromuscular manifestations (Table 2). The onset of symptoms is usually rapid, within minutes to hours after the ingestion. The manifestations may vary from mild to severe. The patient with mild syndrome may have only tachycardia and some autonomic symptoms such as mydriasis, diaphoresis and neurological findings such as hyperreflexia. In severe cases there might be severe hypertension, agitation, delirium and hypertonia. The core temperature has been recorded as high as 41°C in severe cases. The neuromuscular features of clonus and hyperreflexia are highly diagnostic for serotonin syndrome, and their presence in the setting of serotonergic drugs establishes the diagnosis. Clinicians should remember that muscle rigidity could sometimes mask these signs. No laboratory tests confirm the diagnosis of SS. CPK and myoglobin are done to assess the muscle breakdown, secondary to the muscular activity, and rigidity that is seen with this syndrome. Drug screens may help in the detection of co-ingestions that precipitated the syndrome. Measurement of serum serotonin levels has not been shown to be helpful. Sternbach reviewed 38 cases from 10 case reports and 2 case series published in the literature, from which he derived diagnostic criteria for serotonin syndrome (Table 3) [11]. A significant problem with Sternbach’s criteria was the inclusion of four criteria that relate to mental status, i.e., confusion, hypomania, restlessness and incoordination. Because only three were required for the diagnosis of serotonin syndrome, someone with an anticholinergic syndrome would also meet the clinical criteria. Ataxia or incoordination is also not seen in serotonin toxicity since there is no cerebellar involvement. Hunter et al. have described clinical criteria for the diagnosis of this syndrome, which are 84% sensitive and 97% specific for the diagnosis of serotonin syndrome (Fig. 2) [12]. These are currently used to make a diagnosis of serotonin syndrome. Our patient was on a serotonergic agent (fluoxetine) and had inducible clonus with agitation satisfying the Hunter criteria for serotonin syndrome."
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3047867/