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BREAKING OUT OF THE VICODIN PRISON
There is also a biochemical story here that needs to be told and it has to do with an over the counter product that we have always been told is completely safe by the medical establishment (probably ever since we had our first fever as children). Tylenol, otherwise known as acetaminophen is a product that should have been removed from the market decades ago. Why you ask? Because it is toxic to both the brain and liver. In fact, it is the leading cause of acute liver failure world wide.
A 2005 study with several sites across the country found that of 662 patients who met the acute liver failure criteria of coagulopathy and encephalopathy, 42% of these patients (275) had liver failure associated with acetaminophen liver injury. They also noted that the annual percentage of acetaminophen-related failures rose during the study period. Acute liver failure related to use of the painkiller accounted for 28% of all cases in 1998, and 51% in 2003.
Acetaminophen metabolites are toxic to both the liver and the brain by depleting intracellular glutathione. While BIG PHARMA rakes in 2 billion in annual sales WW, that is likely merely a drop in the bucket compared to the undocumented ROI that acetaminophen creates in profit from the various disorders and disease caused by it depleting the body's cellular stores of glutathione.
ACETAMINOPHEN should have NEVER BEEN COMBINED with OPIATES
Why? Because opiates block the cellular uptake of cysteine, which is necessary for glutathione production. Thus, drugs like Vicodin and Norco are pharmacological gulags, making the chronic user hypersensitive to pain due to the combined state of glutathione depletion and tolerance to opiates. Opiates are also pro-inflammatory antigens of the innate immune system.
https://en.wikipedia.org/wiki/Hydrocodone/paracetamol
If you are currently dependent on one of these opiate/acetaminophen "medications", you can take N-acetyl-cysteine (1,200 mg/day), which by passes the opiate block on cellular cysteine uptake. This will help you restore depleted glutathione levels and help you wean off these drugs.
N-acetyl-cysteine (NAC) is the anti-dote used in hospitals to rapidly reverse acute liver failure and is available as aN inexpensive over-the-counter dietary supplement in the US. The reason why N-acetyl-cysteine is the first line treatment to reverse liver toxicity in the emergency room is because the acetyl group allows diffusion across cell membrane without the need of the transporter. Opiate addiction and the hypersensitivity to pain upon withdrawal of opiates is due in large part to being trapped in a state of chronic glutathione deficiency.