State Previous senator New senator
Arizona Republican Party Jeff Flake Democratic Party Kyrsten Sinema
Tennessee Republican Party Bob Corker Republican Party Marsha Blackburn
Utah Republican Party Orrin Hatch Republican Party Mitt Romney
Mississippi Republican Party Thad Cochran Republican Party Cindy Hyde-Smith
Florida Democratic Party Bill Nelson Republican Party Rick Scott
Indiana Democratic Party Joe Donnelly Republican Party Mike Braun
Missouri Democratic Party Claire McCaskill Republican Party Josh Hawley
Nevada Republican Party Dean Heller Democratic Party Jacky Rosen
North Dakota Democratic Party Heidi Heitkamp Republican Party Kevin Cramer