During an October 2015 podcast, Mark Schultz revealed that when John was about 30 years old, a horse he was riding threw him onto a fence, injuring his testicles. They became infected and were removed, resulting in androgynous characteristics for the remainder of his life.

http://www.jewworldorder.org/worlds-scariest-drug-scopolamine/

http://www.ontheblockradio.com/episodes/2015/9/4/episode-4-mark-schultz

du Pont shot and killed Dave Schultz in the driveway of Schultz's home. He said du Pont believed people would break into his house and kill him, and that he had installed a variety of security features in his house.

https://www.nytimes.com/1996/09/22/us/psychiatrists-in-du-pont-murder-case-say-defendant-is-psychotic.html

John du Pont was taking scopolamine at the time of the murder

https://www.reddit.com/r/Documentaries/comments/6l4ayy/worlds_scariest_drug_2012_3543_and_a_coincidence/