Anonymous ID: d6c552 Dec. 30, 2018, 6:25 p.m. No.4529456   🗄️.is 🔗kun

Cannabidiol Cuts Seizures in Resistant Pediatric Epilepsy

 

An FDA-approved, purified form of cannabidiol (Epidiolex, GW Pharmaceuticals) reduces seizure burden in children with drug-resistant epilepsy (DRE), a new review confirms.

 

In a new systematic review of the four randomized controlled trials, few children treated with the cannabis compound experienced complete freedom from seizures or a significant improvement in quality of life.

 

Nonetheless, "we found an increase in the number of children who experienced at least a 50% reduction in seizures, as well as a significant reduction in the frequency of seizures — both of which can be considered a measure of seizure burden," principal investigator Jesse Elliott, PhD candidate at the School of Epidemiology and Public Health, University of Ottawa, Canada, told Medscape Medical News.

 

"This reduction of seizures is an important finding because any reduction in seizures can have a striking impact on the lives of these children and their families," Elliott added.

 

The systematic review, which also included 17 nonrandomized studies, was published online December 4 in Epilepsia.

 

Considerable Burden

About one third of the 50 million patients with epilepsy worldwide live with a drug-resistant form of the condition. This means they failed to respond adequately to two or more antiepileptic-drug regimens.

 

https://www.medscape.com/viewarticle/906665?src=soc_tw_191231_mscpedt_news_neuro_epilepsy&faf=1