Docfag here. Well I'm woke the F up. I had my doubts about adrenochrome but I located this paper from the 50's. It is from the International Review of Neurobiology, a reputable journal. Volume 4, 1962.

THE EFFECT OF ADRENOCHROME AND ADRENOLUTIN ON THE BEHAVIOR OF ANIMALS AND THE PSYCHOLOGY OF MAN By A. Hoffer Psychiatric Services Branch, Department of Public Health, and D epartment of Psychiatry, University of Saskatchewan, Saskatoon, Saskatchewan

In the course of our work on schizophrenia, Dr. Humphry Osmond and I also became interested in epinephrine derivatives which were indoles, as is LSD, rather than sympathomimetic amines like epinephrine or mescaline. In 1952, we presented our epinephrine metabolite hypothesis (adrenochrome) to the Dementia Praecox Committee, Scottish Rite Masons, New York; and in 1954, our first formal report on adrenochrome appeared (Hoffer et al., 1954). The purest preparations of adrenochrome available between 1954 and 1957 were bright red or black powders which were very unstable even when stored under optimal conditions at low temperature and devoid of oxygen. Adrenochrome in aqueous solution deteriorated in minutes and formed insoluble brown-black melanins. Heacock et al. (1958) removed traces of silver ion from the preparations of adrenochrome and formed stable crystals which could be stored at room temperature. Later Heacock and Mahon (1958) synthesized stable adrenolutin and other reduction compounds of adrenochrome (Heacock and Scott, 1959; Heacock and Laidlaw, 1958). A comprehensive chemical review of adrenochrome was made by Heacock (1959a). These chemical studies have greatly facilitated the study of the psychological properties of adrenochrome and its derivatives.

IX. Effect of Adrenochrome and Adrenolutin on Humans Hoffer et al. (1954) observed that adrenochrome produced psychological changes in man. Since then, several additional studies have been recorded but not in great detail. Only the methods used and summaries of results have been given, due to the difficulty in having journals accept long clinical reports. In this review, results of experiments with adrenochrome and adrenolutin will be outlined in greater detail.

>>4752934

D. Adrenochrome Given Sublingually The Taubmann and Jantz method for giving adrenochrome seems most useful. We therefore ran a few trials with crystalline adrenochrome. Since two adrenochromes are known, made from either d- or Z-epinephrine both forms and the dl mixture were tested. 1. Adrenochrome from l-Epinephrine In several studies 6 mg of d-adrenochrome given sublingually produced no change. In one instance, 10 mg produced a change which was very clear and obvious for about 2 days. This case is unusually well documented. The usual adrenochrome changes in perception and thinking resulted. The subject was depressed and irritable, and suffered a marked change in personality. In another case, 3 mg did produce a marked change. After 30 minutes, there was a flush. One and a half hours later, the subject developed strong feelings of isolation. The room became unclear visually and there seemed to be much movement about him. The rest of the day passed without having any sensation of time. In the evening, while in bed, he momentarily hallucinated the face of a person close to him and he became very anxious. In the morning, he was normal. 2. Adrenochrome from d-Epinephrine This was synthesized by R. A. Heacock in 1958. Three mg was given sublingually to two subjects. Subject 1 observed some difficulty in reading and focusing at 7 minutes. At 10 minutes, he was light-headed. At 12 minutes, far objects seemed very far away. At 24 minutes, he was euphoric and could not estimate time. At 35 minutes, time had seemed almost stationary. At 45 minutes, colors were very bright and vivid. At 80 minutes, he was very active in speech and movements and abrupt with people. At 5/2 hours, he felt normal. However, for the next 24 hours, people's faces and other objects would become alternately small and large in size. In one instance, a speaker's face appeared to move away and

>>4752954

toward him. Objects moving toward him increased in size too quickly. Subject 2 also received 3 mg. At 4 minutes, printing on a page became blurred and he had difficulty grasping the meaning of words. At 9 minutes, he became tired and his vision was blurred. At 30 minutes, his thinking was fuzzy. He was apathetic and could not concentrate. The outline of his hand seemed blurred. At 39 minutes, curtains in the room appeared to shimmer. At 52 minutes, he was withdrawn. For the next 30 hours, he was depressed, withdrawn, and disinterested. 3. Adrenochrome from dl-Epinephrine The same subject who had taken 3 mg d-adrenochrome (from Z-epinephrine) took 3 mg <2Z-adrenochrome sublingually. Slight changes in perception (dizziness, light-headedness, increased brightness of room, changes in size of far objects) occurred. There was no change in thought and there was slight euphoria. After 2 hours, he found the experience unpleasant and took 1 gm of nicotinic acid by mouth. That evening, he was irritable, restless, and without ambition. He was bothered by the odor of new wax on the floor, and later by insomnia. The following subjects received 6 mg of di -adrenochrome sublingually. Subject 1 took his adrenochrome at 4:00 Pm. Ten minutes later, he had an anesthetic area over both cheeks and he had difficulty in focusing. At 4:15, he was very quiet and appeared sad but denied this. He underestimated the size of objects about 20%. Three minutes later, he was dizzy as if he would faint. At 4:25, he could no longer estimate passage of time. He thought he had been in all afternoon. His limbs became very light. His hands changed in size as he looked at them and the observer's face changed in size. The rest of the hour, he found paintings unusually vivid. At the end of the hour, he had a headache in the occipital area and felt indifferent. Because of his discomfort, he was given 1 gm of nicotinic acid. In 10 minutes as he began to flush, the perceptual changes vanished and he felt normal. That night, he slept lightly and was not sure whether he had been awake or asleep (twilight sleep). The next morning, he was very tired and considered not coming to work. At work, he Was irritable all day. Subject 2 had had much experience with LSD and was skilled at introspective observation. At 2:00 Pm, he received the adrenochrome. In 5 minutes, he became aware that colors and detail were more distinct. People in pictures seemed more lifelike and larger. In 10 minutes, he had a marked frontal headache. He was able to read but could not make sense out of what he read. At 20 minutes, the visual changes were very clear. He estimated 30 seconds as 45 seconds (mean of 3 trials).

>>4752979

At 25 minutes, he looked older in the mirror. He was relaxed and disinterested. His headache was almost gone but he felt clumsy when moving. One hour after starting he was depressed and irritable. His face was flushed. He was withdrawn and indifferent. While lined up in a cafeteria for coffee, the other people appeared to be puppets. When he drank his coffee, he complained about the noisiness. He felt the people around him were puppetlike, lacked understanding. They annoyed him but he stated he was superior to them. They seemed empty people. At 3:15, his facial flush was gone. The white uniforms of nurses in the cafeteria annoyed him. At 3:40, he thought 2 hours had elapsed since taking adrenochrome. He markedly overestimated size of objects (12 trials). At 2 hours, he felt music was being played at half speed. He likened the experience to the initial symptoms of LSD. It seemed like hours since taking it. His headache was now gone. He reported that the most pleasant part of the experience was that it was wearing off. The next hour, he was easily confused and still could not estimate time correctly. After that he was normal.

>>4752984

E. Potentiation Of The Action Of Adrenochrome Melander and Martens (1958) found that lysergic acid diethylamide (15 to 30 /j-g/kg) and taraxein when given ahead of adrenolutin markedly potentiated its effect. Thus 20-25 mg/kg when given by vein produced only slight changes in cats. But pretreated cats showed a marked response of drowsiness and muscle relaxation after 2-3 mg/kg. Acetyl-LSD also was a potentiator but bromo-LSD was not. Martens et al. (1959c) reported that LSD and taraxein sensitized cats to acetylcholine, epinephrine, atropine, chlorpromazine, histamine, mescaline, and serotonin. They therefore made the sensible suggestion that taraxein, LSD, and (H-acetyl lysergic acid diethylamide (ALD) increase the permeability of these substances through the blood-brain barrier, i.e., they "have the property of enabling certain intravenously injected drugs to act on selected brain centers not normally accessible to them." Hoffer (1959b) and Hoffer and Osmond (1960) found that humans reacted to the combination of LSD followed by adrenochrome or adrenolutin in the same way. There was a marked potentiation of the adrenochrome effect. This was especially notable in human subjects who reacted to LSD primarily by the production of severe tension and anxiety. Visual and psychedelic changes were minimal if present at all. In these subjects, the injection of 10 mg adrenochrome or adrenolutin produced a certain relaxation from tension and the usual LSD experience of marked visual and other changes. Adrenochrome can be used in this way to help break across the tension barrier into the psychedelic experience.

Docfag again, So, it's the real deal. It is found in the blood. It is a metabolite of epinephrin (adrenalin) and can be stabilized. It can be taken orally, under the tongue. This is not a game. I'm trying to figure out how to post the entire journal entry as it's very interdasting but I can't from where I am for certain reasons. I'll get to it.

>>4752987

Sausage

https://www.sciencedirect.com/science/article/pii/S0074774208600252

>>4752977

Fear. This stuff has been synthed since the 50's and why did I not even know about it until a few months ago? I consider myself a pretty good toxicologist and I have seen everything from Angel's Trumpet Seeds (DONT DO IT), to formaldehyde, to bath salts. Never even heard of Adrenochrome. And yet. My concerns are with abortions. I think there are people abusing this stuff. IV and sublingual, likely potentiating with LSD. I'm sure Aleister Crowley did it. Going to dig more on it. For now. It is real. It is intoxicating. It is in fetal blood. It is in children and adult blood. Feel sick now?

>>4753121

Oh, and don't eat Angel's Trumpet seeds. FUCK YOU UP!

https://www.ncbi.nlm.nih.gov/pubmed/16783491

Anyone play Far Cry Five?