Glass & Gold
https://m.phys.org/news/2019-02-skin-wound-regeneration-bioactive-glass-gold.html
http://archive.is/s07F7
>Angiogenesis, or the formation of new blood vessels from existing vessels is an important process during skin regeneration. Bioactive glass is responsible for local cellular responses due to in vivo degradation, stimulating the release of growth factors such as VEGF (vascular endothelial growth factor) and bFGF (basic fibroblast growth factor) to cause an angiogenic effect. A variety of studies on tissue engineering have demonstrated the benefits of bioactive glass in wound healing, based on results in animal models in vivo. In its principle of action, scientists have reported that bioactive glass stimulated the process by controlling the inflammation response to enhance the paracrine effect between macrophages and repairing cells.
>Gold nanoparticles (AuNPs) are similarly becoming important in medicine due to their chemical and physical properties of biocompatibility, surface modification, stability and optical properties. Despite their challenging early translation in tissue engineeringapproaches, a low concentration of AuNPs can stimulate cell proliferation during wound repair. Preceding studies by the same research team showed that bioactive glass with AuNPs could stimulate the proliferation of human keratinocyte cells (HaCaT), which constitute 95 percent to 97 percent of the epidermis on the skin surface. In the present study, Marza et al. investigated the potential of dermal tissue regeneration in vivo. By day 14, they observed that both BG and BG-AuNP-Vaseline ointments could stimulate complete skin regeneration in experimental rat models, substantiated with gold standard histopathological analyses.