The 25th amendment of the US constitution lays out the procedure for the Vice President and a majority of Cabinet members to remove a sitting president from office.
Under the amendment's fourth stipulation, it would only take 14 people to depose the president - Vice President Mike Pence and 13 of Trump's 24 Cabinet members.
Cabinet members had-have to be rotated for a reason. Sudden movement to remove traitors in the cabinet would look irrational and unstable. Neutralize those still in power and control them.