Anonymous ID: c5fe21 Feb. 21, 2019, 12:26 p.m. No.5308228   🗄️.is 🔗kun   >>8249 >>8286 >>8329 >>8821

gene flow

 

Brett Payseur is into this:

 

n.

Transfer of genes from one population to another, as by migration or the dispersal of seeds and pollen.

 

https://journals.plos.org/plosgenetics/article?id=10.1371/journal.pgen.0030090

 

Author Summary

 

A selective sweep is a single realization of adaptive evolution at the molecular level.When a selective sweep occurs, it leaves a characteristic signal in patterns ofvariation in genomic regions linked to the selected site; therefore, recently releasedpopulation genomic datasets can be used to search for instances of molecular adaptation.Here, we present a comprehensive scan for complete selective sweeps in the human genome.Our analysis is complementary to several recent analyses that focused on partialselective sweeps, in which the adaptive mutation still segregates at intermediatefrequency in the population. Consequently, our analysis identifies many genomic regionsthat were not previously known to have experienced natural selection, includingconsistent evidence of selection in centromeric regions, which is possibly the result ofmeiotic drive. Genes within selected regions include pigmentation candidate genes, genesof the dystrophin protein complex, and olfactory receptors. Extensive testingdemonstrates that the method we use to detect selective sweeps is strikingly robust toboth alternative demographic scenarios and recombination rate variation. Furthermore,the method we use provides precise estimates of the genomic position of the selectedsite, which greatly facilitates the fine-scale mapping of functionally significantvariation in human populations.

 

Citation: Williamson SH, Hubisz MJ, Clark AG, Payseur BA, Bustamante CD, Nielsen R (2007) Localizing Recent Adaptive Evolution in the Human Genome. PLoS Genet 3(6): e90.https://doi.org/10.1371/journal.pgen.0030090

 

https://onlinelibrary.wiley.com/doi/full/10.1111/mec.13557

 

Editor: Gil McVean, University of Oxford, United Kingdom

 

https://payseur.genetics.wisc.edu/