Anonymous ID: 9e19cb April 22, 2019, 3:54 p.m. No.6277361   🗄️.is 🔗kun   >>7370 >>7402 >>7711

https://medium.com/s/meghan-daum/male-and-female-brains-are-different-should-it-matter-6db82ead5e20

http://archive.is/28s5z

 

Male and Female Brains Are Different

Neuroscientist Larry Cahill on the great ‘neurosexism’ debate

 

In a major policy change implemented in early 2016, the National Institutes of Health made clear its expectation that researchers seeking grants "consider sex as a biological variable in all stages of research"

"Can We Finally Stop Talking About ‘Male’ and ‘Female’ Brains?" went the headline of a 2018 New York Times op-ed by two prominent figures on the anti-sex difference side of the debate. The journal Nature, which less than a decade ago was routinely publishing articles that acknowledged the presence of genetic sex differences in the brain and other organs, ran an article in its February 27, 2019, issue entitled "Neurosexism: The Myth That Men and Women Have Different Brains." The piece was a book review of The Gendered Brain: The New Neuroscience That Shatters the Myth of the Female Brain by Gina Rippon, a professor of cognitive neuroimaging in the U.K.

 

When neuroscientist Larry Cahill read the article, his first response was, "You’ve got to be kidding me."

Cahill doesn’t do a lot of writing for lay publications. But on March 29, he published an article in Quillette entitled "Denying the Neuroscience of Sex Differences." In it, he laid out some of the history of the field (it’s a short history, he says, since until about two decades ago, few people even thought to study the differences) and pointed out the inherent fallacy of equating such research with neurosexism. "By constantly denying and trivializing and even vilifying research into biologically-based sex influences on the brain," he wrote, "[the anti-sex difference contingent is] in fact advocating for biomedical research to retain its male subject-dominated status quo so disproportionately harmful to women.

You say in the article that, for decades, neuroscientists-yourself included-used only male research subjects because they assumed females were identical.

Why was this the case, and what changed?

 

Like everyone else in neuroscience, I used to fully believe that there weren’t any sex differences or influences on brain function, with the exception of little-bitty brain parts explicitly associated with sex and sex hormones and sex parts. Those parts are different in males and females-okay, fine. But when you move beyond those little-bitty regions at the base of the brain, all of us, myself included, assumed that there were not fundamental sex differences, that they didn’t exist. This was the case no matter what we were studying: amygdala and emotion, the hippocampus and memory, the prefrontal cortex and working memory, vision-you name it. That’s precisely why we all studied males. The view was that if you want to understand the female, then, ironically, the best way to understand the female was to study the male. For most neuroscientists, the rationale was not a sexist rationale. It was the opposite. The rationale was there aren’t any differences between males and females, so you avoid the unnecessarily complicated feature of the female hormonal cycle and study the male.

continued…

Anonymous ID: 9e19cb April 22, 2019, 3:55 p.m. No.6277370   🗄️.is 🔗kun

>>6277361

continued…

What kinds of discoveries were made over the past 20 years?

 

In the past, we just assumed there were no differences, so we didn’t bother looking. Now it’s the complete opposite. More and more dominoes are falling. More and more neuroscientists are saying, "Wow, if I’m studying the hippocampal synapse-the center of the field of brain memory-in rats, I’m seeing that it’s operating somewhat differently in the male than in the female." Once you discover this, you can’t pretend it’s not true. You can’t go, "Oh, it’s a bunch of bullshit, and I hear it’s neurosexist."

But we know exactly what it means on a fundamental level, which is that a foundational assumption of how we did neuroscience is wrong and has to change. A foundational assumption of how I spent the first 20 years of my career doing science was wrong.

 

What exactly are you trying to change?

 

I’ve spent the past 20 years of my career basically saying to my neuroscience colleagues and all of medicine-that means immunologists and cardiologists and everybody-"Hey, guys, you may not believe it, but there are sex influences all over the damn place. And you simply cannot be treating women equally by ignoring them." This has been my mantra for 20 years now. This is something that I think people outside of science have trouble grasping.

 

One of the arguments by those who are made nervous about this kind of research is that the information could be twisted or misused for harmful purposes, sort of like how evolutionary psychology can get extrapolated into reductive and sexist conclusions about mating rituals and gender roles.

What do you say to that?

 

Yes, that is one of their arguments. I say by that logic we shouldn’t study genetics. We’re not going back to the Dark Ages. [The German philosopher] Arthur Schopenhauer said there are three phrases to the acceptance of any truth: First, the truth is ridiculed. Second, it’s opposed. Third, it’s accepted as self-evident. I spent much of the past 20 years in the ridicule phase: "Oh, Larry Cahill, you used to do such good work. Now he’s studying the sex-differences bullshit!"

 

But it’s reached a critical mass now where both within neuroscience and outside of it, it’s getting scary for people who believe there can’t be sex differences in brain. So, now we’re in phase two, which is fighting it. I tell people to stay away from the ideologues on both sides of the issue. Stay away from the ones who tell you, "There’s male and there’s female and never the two shall meet." But also stay away from the ideologues on the other side, who unfortunately are given a voice by editors at places like the New York Times, who know nothing about the issue except that they’re afraid of appearing to be on the wrong side of it.

What’s an example of the kind of evidence for sex differences that your students find surprising?

 

One of the things that blows students’ minds is to realize that women disproportionately, about twice as much, suffer from all anxiety and depression disorders relative to men, and almost all our models for studying anxiety disorders are based on male animals. Even in those cases where the results in the male animal don’t necessarily generalize to the female animal, we still use them as models for human depression and anxiety disorders.

The ancient Romans had an expression: Quod volumus, facile credimus. "We readily believe what we want to believe."

I wish we’d grow out of that as a species.

Anonymous ID: 9e19cb April 22, 2019, 4:19 p.m. No.6277711   🗄️.is 🔗kun

>>6277361

plus the underlying article:

Denying the Neuroscience of Sex Differences

by Larry Cahill

 

https://quillette.com/2019/03/29/denying-the-neuroscience-of-sex-differences/

http://archive.is/hqM8J

 

A review of The Gendered Brain: The new neuroscience that shatters the myth of the female brain, by Gina Rippon. The Bodley Head Ltd (March 2019).

 

Imagine your response to picking up a copy of the leading scientific journal Nature and reading the headline: “The myth that evolution applies to humans.” Anyone even vaguely familiar with the advances in neuroscience over the past 15–20 years regarding sex influences on brain function might have a similar response to a recent headline in Nature: “Neurosexism: the myth that men and women have different brains” subtitled “the hunt for male and female distinctions inside the skull is a lesson in bad research practice.”