We know what part of Florida is the most crazy and least comfy - Broward.
Keys are nice and relaxed.
Panhandle and north Florida is southern in flavor. Not as many retirees. There are quiet out of the way areas, Atlantic coast above St Augustine or Gulf coast north of Citrus County.
Miami area feels materialistic. Orlando feels touristy. Tampa has lots of retirees. Daytona has surfers. Gainesville as students. Brevard County has some aerospace / tech.
Inland central florida, away from the Orlando metro region, is more agricultural. But also feels gritty in a way.
But if you're in Florida, you can't really get too far away from Florida Man.