>>7604192 (pb)

Computational biofag here. The major histocompatibility complex (MHC) is THE genetic region that contains 3 pairs of genes for histocompatibility – "histo":tissue, compatibility. This is precisely what has to be matched for…

…wait for it…

ORGAN TRANSPLANTATION

Weirdo responsible for HLA typing thousands of Han Chinese caught stealing... what? Nothing wrong here...

https://www.ncbi.nlm.nih.gov/books/NBK27163/

Responses to alloantigens and transplant rejection

The transplantation of tissues to replace diseased organs is now an important medical therapy. In most cases, adaptive immune responses to the grafted tissues are the major impediment to successful transplantation. Rejection is caused by immune responses to alloantigens on the graft, which are proteins that vary from individual to individual within a species, and are thus perceived as foreign by the recipient. In blood transfusion, which was the earliest and is still the most common tissue transplant, blood must be matched for ABO and Rh blood group antigens to avoid the rapid destruction of mismatched red blood cells by antibodies (see Appendix I, Section A-11). Because there are only four major ABO types and two Rh blood types, this is relatively easy. When tissues containing nucleated cells are transplanted, however, T-cell responses to the highly polymorphic MHC molecules almost always trigger a response against the grafted organ. Matching the MHC type of donor and recipient increases the success rate of grafts, but perfect matching is possible only when donor and recipient are related and, in these cases, genetic differences at other loci still trigger rejection.

>>7605466

Anyone have the link to the story about live all-organ donation without anesthesia?

Anyone have the video with humans on meathooks in a refrigerated truck?

>>7605632

If Engrish were your first language, you'd know how to spell "allegiance".

>>7605805

On the military warning about DNA – this is why (among other things):

>>7604192 (pb)

Computational biofag here. The major histocompatibility complex (MHC) is THE genetic region that contains 3 pairs of genes for histocompatibility – "histo":tissue, compatibility. This is precisely what has to be matched for…

ORGAN TRANSPLANTATION

https://www.ncbi.nlm.nih.gov/books/NBK27163/

Responses to alloantigens and transplant rejection

The transplantation of tissues to replace diseased organs is now an important medical therapy. In most cases, adaptive immune responses to the grafted tissues are the major impediment to successful transplantation. Rejection is caused by immune responses to alloantigens on the graft, which are proteins that vary from individual to individual within a species, and are thus perceived as foreign by the recipient. In blood transfusion, which was the earliest and is still the most common tissue transplant, blood must be matched for ABO and Rh blood group antigens to avoid the rapid destruction of mismatched red blood cells by antibodies (see Appendix I, Section A-11). Because there are only four major ABO types and two Rh blood types, this is relatively easy. When tissues containing nucleated cells are transplanted, however, T-cell responses to the highly polymorphic MHC molecules almost always trigger a response against the grafted organ. Matching the MHC type of donor and recipient increases the success rate of grafts, but perfect matching is possible only when donor and recipient are related and, in these cases, genetic differences at other loci still trigger rejection.