Massive hug, longtime fren.
I don't know. Tell you my routine & you decide.
When I'm focusing on memeharvesting I do harvest as many of the good ones as I can from breads. There are distractions in my life … so this activity is sporadic not continual … I process them about once a day or so and post in the memes bread, then move to an upload folder. Then I collect memes from the memes bread that I haven't seen. I archive most of them, not all. (I have my limits!) Process the 2nd set of collected memes (compress, shrink, Trimage) & put THAT batch in the upload folder. Then upload to Mega.
So if it's not in the Memes bread and I'm not watching, I might miss it. Eventually the great memes come around again and there's a 2nd chance of harvesting them.
I get tired sometimes or need a break.