Anonymous ID: ded75b Dec. 30, 2019, 7:52 a.m. No.7662452   🗄️.is 🔗kun   >>2580 >>2643

>>7662287

Synergistic co-administration of computationally optimized broadly reactive antigens for human and avian h5n1 influenza

https://patents.google.com/patent/US20190111126A1/en

Inventor

Ted Milburn Ross

Tim Alefantis

Donald Martin Carter

Christopher Austin Darby

Abstract

The present invention provides co-administration (e.g., immunogenic cocktail and/or prime-boost regimens) of computationally optimized H5N1 influenza hemagglutinin (HA) polypeptides that. Co-administration of the optimized H5N1 influenza hemagglutinin (HA) polypeptides facilitates synergistic neutralization of viral infection and provides for improved protective immunity (e.g., a broad reactive immune response) to multiple H5N1 influenza virus clades and strains.

https://patents.google.com/?inventor=Tim+Alefantis

Harold Kleanthous

Current Assignee Oregon Health Science University

Sanofi Pasteur Inc

 

https://patents.google.com/?inventor=Tim+Alefantis