The only difference is production value.
You'll get a range of sizes no matter how it's produced, and the better you are at it the better the product.
By technical definition, all reduced silver - no matter the size - is colloidal.
All 'clear' silver, is a hydrosol - ions dissolved in water.
A colloid is a particle indefinitely suspended in water, not dissolved in water.
The size = the quality, and you can make what cured that persons syndrome from your own home.
There's plenty of shilling + ignorance around silver…