Erica Bickerton

Coronavirus

Patent number: 10130701

Abstract: The present invention provides a live, attenuated coronavirus comprising a variant replicase gene encoding polyproteins comprising a mutation in one or more of non-structural protein(s) (nsp)-10, nsp-14, nsp-15 or nsp-16. The coronavirus may be used as a vaccine for treating and/or preventing a disease, such as infectious bronchitis, in a subject.

Type: Grant

Filed: July 23, 2015

Date of Patent: November 20, 2018

Assignee: THE PIRBRIGHT INSTITUTE

Inventors: Erica Bickerton, Sarah Keep, Paul Britton

Im diggin on this