Anonymous ID: 2dfd3b Feb. 3, 2020, 1:13 a.m. No.8009236   ๐Ÿ—„๏ธ.is ๐Ÿ”—kun   >>9304 >>9468 >>9616 >>9671 >>9705 >>9715

>>8009219

>>8009228

 

>What does that even mean?

 

Exactly what it sounds like it means.

 

This is why the Chinese have been using AIDS testing kits and AIDS medications for this outbreak.

 

This PDF has been heavily censored.

 

Uncanny similarity of unique inserts in the 2019-nCoV spike protein to HIV-1 gp120

and Gag

 

Abstract:

We are currently witnessing a major epidemic caused by the 2019 novel coronavirus (2019-

nCoV). The evolution of 2019-nCoV remains elusive. We found 4 insertions in the spike

glycoprotein (S) which are unique to the 2019-nCoV and are not present in other coronaviruses.

Importantly, amino acid residues in all the 4 inserts have identity or similarity to those in the HIV1 gp120 or HIV-1 Gag. Interestingly, despite the inserts being discontinuous on the primary

amino acid sequence, 3D-modelling of the 2019-nCoV suggests that they converge to constitute

the receptor binding site. The finding of 4 unique inserts in the 2019-nCoV, all of which have

identity /similarity to amino acid residues in key structural proteins of HIV-1 is unlikely to be

fortuitous in nature. This work provides yet unknown insights on 2019-nCoV and sheds light on

the evolution and pathogenicity of this virus with important implications for diagnosis of this virus.

Introduction

Coronaviruses (CoV) are single-stranded positive-sense RNA viruses that infect animals and

humans. These are classified into 4 genera based on their host specificity: Alphacoronavirus,

Betacoronavirus, Deltacoronavirus and Gammacoronavirus (Snijder et al., 2006). There are seven

known types of CoVs that includes 229E and NL63 (Genus Alphacoronavirus), OC43, HKU1,

MERS and SARS (Genus Betacoronavirus). While 229E, NL63, OC43, and HKU1 commonly

infect humans, the SARS and MERS outbreak in 2002 and 2012 respectively occurred when the

virus crossed-over from animals to humans causing significant mortality (J. Chan et al., n.d.; J. F.

W. Chan et al., 2015). In December 2019, another outbreak of coronavirus was reported from

Wuhan, China that also transmitted from animals to humans. This new virus has been temporarily

termed as 2019-novel Coronavirus (2019-nCoV) by the World Health Organization (WHO) (J. F.-

W. Chan et al., 2020; Zhu et al., 2020). While there are several hypotheses about the origin of

2019-nCoV, the source of this ongoing outbreak remains elusive.

The transmission patterns of 2019-nCoV is similar to patterns of transmission documented in the

previous outbreaks including by bodily or aerosol contact with persons infected with the virus.

It is made available under a CC-BY-NC-ND 4.0 International license.

preprint (which was not peer-reviewed) is the author/funder, who has granted bioRxiv a license to display the preprint in perpetuity.

bioRxiv preprint first posted online Jan. 31, 2020; doi: http://dx.doi.org/10.1101/2020.01.30.927871. The copyright holder for this

Cases of mild to severe illness, and death from the infection have been reported from Wuhan. This

outbreak has spread rapidly distant nations including France, Australia and USA among others.

The number of cases within and outside China are increasing steeply. Our current understanding

is limited to the virus genome sequences and modest epidemiological and clinical data.

Comprehensive analysis of the available 2019- nCoV sequences may provide important clues that

may help advance our current understanding to manage the ongoing outbreak.

The spike glycoprotein (S) of cornonavirus is cleaved into two subunits (S1 and S2). The S1

subunit helps in receptor binding and the S2 subunit facilitates membrane fusion (Bosch et al.,

2003; Li, 2016). The spike glycoproteins of coronoviruses are important determinants of tissue

tropism and host range. In addition the spike glycoproteins are critical targets for vaccine

development (Du et al., 2013). For this reason, the spike proteins represent the most extensively

studied among coronaviruses. We therefore sought to investigate the spike glycoprotein of the

2019-nCoV to understand its evolution, novel features sequence and structural features using

computational tools.

Anonymous ID: 2dfd3b Feb. 3, 2020, 1:26 a.m. No.8009267   ๐Ÿ—„๏ธ.is ๐Ÿ”—kun   >>9270 >>9279 >>9337 >>9345 >>9404 >>9468 >>9616 >>9671 >>9694 >>9705 >>9715

NOTHING TO SEE HERE FOLKS, PLEASE MOVE ALONG

 

Statement about nCoV and our pandemic exercise

In October 2019, the Johns Hopkins Center for Health Security hosted a pandemic tabletop exercise called Event 201 with partners, the World Economic Forum and the Bill & Melinda Gates Foundation. Recently, the Center for Health Security has received questions about whether that pandemic exercise predicted the current novel coronavirus outbreak in China. To be clear, the Center for Health Security and partners did not make a prediction during our tabletop exercise. For the scenario, we modeled a fictional coronavirus pandemic, but we explicitly stated that it was not a prediction. Instead, the exercise served to highlight preparedness and response challenges that would likely arise in a very severe pandemic. We are not now predicting that the nCoV-2019 outbreak will kill 65 million people. Although our tabletop exercise included a mock novel coronavirus, the inputs we used for modeling the potential impact of that fictional virus are not similar to nCoV-2019.

 

http://www.centerforhealthsecurity.org/newsroom/center-news/2020-01-24-Statement-of-Clarification-Event201.html

Anonymous ID: 2dfd3b Feb. 3, 2020, 2:04 a.m. No.8009353   ๐Ÿ—„๏ธ.is ๐Ÿ”—kun   >>9356

>>8009345

 

>Hope stuff leaks to test this claim.

 

Stuff was already out about it, and then (((they))) scrubbed it down to this.

 

Apparently many sauce links suddenly got dead-ended or pointed to the official statement, and that's all anyone can find anymore.

 

Maybe a good dig for curious Anons.

Anonymous ID: 2dfd3b Feb. 3, 2020, 2:50 a.m. No.8009486   ๐Ÿ—„๏ธ.is ๐Ÿ”—kun   >>9513

>>8009470

 

>You would need to see the original text to see what he really said. English-Greek would be best.

 

I translated Greek from Homer to Aristophanes to Plato to Aristotle to Plutarch on down to koine NT. Not that such expertise is necessary to understand what he did. The ancient classical world broadly understood that the Earth is a spherical planet. The very rationale behind his measurements presupposed a globe.