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https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3767196/
In vitro antiviral activity of neem (Azardirachta indica L.) bark extract against herpes simplex virus type-1 infection
We report here that an aqueous extract preparation from the barks of neem plant Azardirachta indica acts as a potent entry inhibitor against HSV-1 infection into natural target cells. The extract from neem bark (NBE) significantly blocked HSV-1 entry into cells at concentrations ranging from 50 to 100 μg/ml. The blocking activity of NBE was observed when the extract was pre-incubated with the virus but not with the target cells suggesting a direct anti-HSV-1 property of the neem bark.