This is an extremely dangerous pathogen with wide spreading implications, including neurological impairment, brain, lung, heart & reproductive damage.
There are now two recognized strains of the disease. The L strain is more infectious and severe than the ancestral S strain.
The disease has an R0 of around 6.6, which means 1 person infects that many other people, on average.
The median incubation period is around 5 days, but outliers of 24+ days have been seen.
The ability of the virus to stay active on surfaces for up to 27 days is also a cause for significant concern.
SARS-CoV-2 is spreading at alarming levels due to its ability to be airborne.
SARS-CoV-2 is capable of asymptomatic transmission and it is practically impossible to stop the spread by contact tracing and minor quarantines. There are a multitude of asymptomatic carriers walking around.
SARS-CoV-2 can enter the eye through the ocular surface. Any protective mask must be full-face. Half-face masks are insufficient.
The virus attacks ACE2 receptors in cells. it's part of the angiotensin-renin system that regulates vasoconstriction and vasodilation.
This system is essential for your body to maintain the correct blood pressure. ACE2 receptors are found in many vital organs and reproductive tissues in the human body — Lungs, heart, kidneys, & brain.
SARS-CoV-2 infection also has severely negative effects on male fertility. ACE2 receptors are found in the seminiferous ducts of the testis.
SARS-CoV-2 can potentially cause lung fibrosis and chronic lung disease if not caught and treated with antivirals at an early stage. This has serious implications for treatment of patients who get infected with a different strain; their weakened condition may increase mortality.
SARS-CoV (a relative of SARS-CoV-2) has been shown to cause severe neural death (surprisingly without encephalitis) in transgenic mouse models.
Recent information seems to suggest that SARS-CoV-2 can cause neurological symptoms and cerebrovascular disease, leading to loss of autonomic functions of the brain and, in the worst case, lingering brain damage.
This could cause a significant portion of the population to have severe drops in cognitive function, intelligence, and IQ.
The action of SARS-Coronaviruses (which attack ACE2 pathways) can dysregulate the angiotensin system and cause cardiopulmonary damage and inflammation directly through this route.
SARS-CoV-2 can cause myocarditis leading to myoglobin accumulation in the blood and renal failure. It can also directly attack several vital organs of the body.
What disturbs me the most about this virus is that it can potentially target so many different kinds of tissues. If, for instance, it attacks ACE2 in the neurons and leads to brain death and seizures.
There are so many different things that could cause the collapses we have witnessed. Febrile seizures from fever, heart attacks due to myocarditis, or even fainting from hypoxia from pneumonia.
However, what I found most concerning about the collapses is the consistent presentation of the victim; the rigidity of the body and the seizures. You would think there would be postural variations. Someone having a heart attack would struggle, they would bend their knees…
These people, their limbs stretch out straight, and they begin to seize or show the fencing sign. At first, I suspected cerebral vasculitis caused by the virus attacking blood vessels in the brain, or viral encephalitis attacking the brain tissue directly.
Imagine my surprise when it was discovered that in transgenic mouse models (hACE2 mice), SARS-CoV can cause neuronal damage without apparent encephalitis.
Coronavirus does not just effect the respiratory system, it embeds itself into the central nervous system & has the potential to cause significant neurological impairment, brain damage, & cancer.
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