Anonymous ID: ac6efc March 22, 2020, 2:19 p.m. No.8520658   🗄️.is đź”—kun   >>0684 >>2426

Dysmetabolic Iron Overload Syndrome (DIOS)

is characterized by an elevated serum ferritin with a normal transferrin-iron saturation percentage. People with DIOS will likely also have an elevated GGT (liver enzyme) possibly due to a fatty liver. Individuals with DIOS are helped by phlebotomy, diet and exercise. The FeGGT test is helpful in determining the iron status and GGT status. For more information about GGT and the FeGGT test, visit HealtheIron.com

 

About Overload

Iron overload is an excess (too much) iron in the body. Excess iron in vital organs, even in mild cases of iron overload, increases the risk for liver disease (cirrhosis, cancer), heart attack or heart failure, diabetes mellitus, osteoarthritis, osteoporosis, metabolic syndrome, hypothyroidism, hypogonadism, numerous symptoms and in some cases premature death. Iron mismanagement resulting in overload can accelerate such neurodegenerative diseases as Alzheimer’s, early-onset Parkinson’s, Huntington’s, epilepsy and multiple sclerosis.

 

Iron overload can be inherited (genetic) or acquired by receiving numerous blood transfusions, getting iron shots or injections, or consuming high levels of supplemental iron. Some of the genetic disorders that result in iron overload include are hereditary hemochromatosis (all types), African iron overload, sickle cell disease, thalassemia, X-linked sideroblastic anemia, enzyme deficiencies (pyruvate kinase; glucose-6-phosphate dehydrogenase) and very rare protein transport disorders aceruloplasminemia and atransferrinemia. None of these conditions should be confused with polycythemia vera (PV), which is not an iron disorder, but a condition where the bone marrow produces too many blood cells (red, white and platelet). People with PV have abnormally high hemoglobin and are at risk for a stroke and progressing to acute myelogenous leukemia (AML). Part of the therapy for PV is phlebotomy.

 

Symptoms, signs and diseases resulting from too much iron (iron overload):

 

chronic fatigue

joint pain

abdominal pain

liver disease (cirrhosis, liver cancer)

diabetes mellitus

irregular heart rhythm

heart attack or heart failure

skin color changes (bronze, ashen-gray green)

loss of period

loss of interest in sex

osteoarthritis

osteoporosis

hair loss

enlarged liver or spleen

impotence

infertility

hypogonadism

hypothyroidism

hypopituitarism

depression

adrenal function problems

early onset neurodegenerative disease

elevated blood sugar

elevated liver enzymes

elevated iron (serum iron, serum ferritin)

 

The treatment for iron overload is iron reduction therapy. A person's hemoglobin is key in the physician's decision of iron reduction therapy. If the patient's hemoglobin level is sufficient to tolerate blood removal (phlebotomy), the doctor can provide either an order for therapeutic phlebotomies or can recommend that a patient routinely donate blood. When a patient's hemoglobin is too low for phlebotomy, iron reduction will likely require iron-chelation, which is the removal of iron using specific drugs. In some situations the physician may use a combination of these two therapies.

Anonymous ID: ac6efc March 22, 2020, 2:26 p.m. No.8520792   🗄️.is đź”—kun   >>0821

Iron overload disorders are a group of medical conditions that cause the body to store excess iron. They include hereditary hemochromatosis, a genetic condition in which a person’s body absorbs too much iron from foods and drinks.

 

The body cannot excrete excess iron, so it stores it in certain organs, notably the liver, heart, and pancreas, which can lead to organ damage. Damage to the pancreas can cause diabetes. Excess iron can, without treatment, also turn the skin a bronze color.

 

With treatment, people with this condition have a good outlook. Treatments may include drawing blood to reduce the body’s iron levels and making dietary changes to reduce iron intake.

 

In this article, we look at the types, causes, symptoms, and treatment of iron overload disorder.

 

In a healthy body, when the stores of iron are sufficient, the intestines reduce the absorption of this mineral from food and drink to prevent its levels from rising too high.

 

People with iron overload disorders absorb more iron than usual from food or supplements. The body cannot excrete the extra iron fast enough, so it continues to build up. The body stores it in organ tissue, mainly in the liver, as well as the heart and the pancreas.

 

There are several types of iron overload disorder. Hereditary hemochromatosis is a primary condition that has a genetic component. People can also have secondary hemochromatosis, which develops as a result of another disease or condition.

 

Pancreas - Steve Jobs, Patrick Swayze, RBG, see a pattern here?