Why is David Spade so desperate to hear from Tom Hanks?
Because Hanks and Wilson are undergoing experimental treatment in a desperate attempt to cure them from the strain of the virus caused by ingesting the Wuhan adrenochrome.
All their hopes hang on this. They hoped to know within two weeks. Hanks just gave an update.
Meanwhile they’re all losing their minds as they wait. Time is ticking. Either they wait it out in this hope for a cure or they go get medical help but in so doing out themselves and will be prosecuted.