Chlorquine works only in combination with Zinc. Chloroquine is the ionophore that gets the zinc into the cells. In vitro the zinc will destroy most viruses up to and including Hepatitis C. It's actually the zinc that does the job. Here are the NIH studies:

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2973827/

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4182877/