Anonymous ID: 6ec333 April 12, 2020, 4:36 p.m. No.8772737   ๐Ÿ—„๏ธ.is ๐Ÿ”—kun   >>2783 >>2814 >>2884 >>2970 >>2979 >>3027 >>3030

>>8772490

Couldn't find any good sauce that grapefruit contains quinine.

Here are several resources/tables with nutrients:

https://fdc.nal.usda.gov/fdc-app.html#/food-details/174673/nutrients

http://www.whfoods.com/genpage.php?tname=foodspice&dbid=25

https://www.nutrition-and-you.com/grapefruit.html

 

None of them mention quinine. In a paper about whole plant nutrients:

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3059462/

quinine is mentioned but not in connection with grapefruit (though it seems to have other components helpful in malaria treatment).

A second paper studies the properties of grapefruit's influence on metabolism of quinine:

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3059462/

and little/no significant effect was found.

This also indicates that grapefruit does not contain quinine.

 

The link fruitjuicefocus.com says:

โ€˜The juice or grapefruit itself contains valuable and natural quinine, which is advantageous for the treatment of malariaโ€™

a direct quote from another article:

https://www.organicfacts.net/health-benefits/fruit/health-benefits-of-grapefruit.html

which cites the "whole plant nutrients" paper mentioned above, where no quinine in grapefruits is mentioned.

Anonymous ID: 6ec333 April 12, 2020, 4:45 p.m. No.8772812   ๐Ÿ—„๏ธ.is ๐Ÿ”—kun   >>2831 >>2841 >>2868 >>2970

>>8772783

If you had read just a couple of lines from the papers I have mentioned above, you'd have come across CYP3A4, an enzyme that metabolizes quinine in the liver.

Grapefruit does have CYP3A4, thus the warning not to cross-consume, because the body could be unable to metabolize quinine (i.e. remove it).

Above paper

https://www.ncbi.nlm.nih.gov/pubmed/10456490

clearly says that grapefruit has no (or only little) effect on quinine pharmacokinetics.

 

Grapefruit does not contain quinine.