UC San Francisco
epicenterof loads of research fukkery
Brian Black, PhD
Professor of Biochemistry
Investigator, Cardiovascular Research Institute
Graduate Program Membership: BMS, DSCB, Tetrad
Website | UCSF Faculty Profile
https://humangenetics.ucsf.edu/our-research/faculty/
Brian Black, PhDDr. Black’s research program focuses on transcriptional control of organogenesis to understand normal development, the molecular basis for congenital defects, and potential mechanisms for organ regeneration and repair. Using mouse as a model system, his current efforts are aimed at understanding pathways that control cardiovascular and craniofacial development. Using a combination of conditional gene knockouts, transgenic reporter assays, and biochemical, genomic and computational approaches, he is defining how tissues and cells are organized during organogenesis and how cells receive and interpret positional information. The ultimate goal is to develop diagnostic and therapeutic interventions.
what is organogenesis?
Process of organogenesis
Organogenesis. Organogenesis is the process by which the three germ tissue layers of the embryo, which are the ectoderm, endoderm, and mesoderm, develop into the internal organs of the organism. … The ectoderm forms epithelial cells and tissues, as well as neuronal tissues.
Who would want to control this?
What is transcriptional control?
In molecular biology and genetics, transcriptional regulation is the means by which a cell regulates the conversion of DNA to RNA (transcription), thereby orchestrating gene activity.
transcriptional control