I watched Dune again today and noted some interesting concepts. Three major factions. The spacing guild, the Bene Gesserit and the emperor. I thought it was interesting how the spacing guild had more power than the emperor. They controlled him and told him what he could and could not do.
The spice must flow.
Melange (fictional drug)
Melange (/meɪˈlɑːnʒ/),[1] often referred to as simply "the spice", is the name of the fictional drug central to the Dune series of science fiction novels by Frank Herbert, and derivative works.
In the series, the most essential and valuable commodity in the universe is melange, a drug that gives the user a longer life span, greater vitality, and heightened awareness; it can also unlock prescience in some humans, depending upon the dosage and the consumer's physiology. This prescience-enhancing property makes safe and accurate interstellar travel possible. Melange comes with a steep price, however: it is addictive, and withdrawal is fatal. Harvesting melange is also hazardous in the extreme, as its only known source is the harsh desert planet Arrakis, and melange deposits are guarded by giant sandworms.
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https://en.wikipedia.org/wiki/Melange_(fictional_drug)
Sound familiar? Spice/adrenochrome?