Hydroxychloroquine is the synthetic version of Quinine…

Quinine is a medication used to treat malaria. Quinine was first isolated in 1820 from the bark of a cinchona tree, which is native to Peru.

According to tradition, because of the bitter taste of anti-malarial quinine tonic, British colonials in India mixed it with gin to make it more palatable, thus creating the gin and tonic cocktail…

https://en.m.wikipedia.org/wiki/Quinine

Another link about Quinine.

THE HISTORY OF QUININE

Quinine has been used for centuries to treat malaria. Derived from the bark of the Cinchona or ‘fever tree’, quinine has proved a highly effective treatment against the malaria parasite for over 350 years.

However, it was during the 1800s that British troops in India were given quinine to take as a daily medicine to stop them contracting Malaria.

Quinine is a bitter substance and so to help ‘the medicine go down’, they mixed it with water, sugar and local fruits and, in doing so, created the first tonic water. However, the British troops also always carried a ration of gin with them. So, with their officers' permission, they added an expedient of gin to their daily tonic and thus was born the gin and tonic that is so beloved today.

Since Victorian times, methods of abating malaria and treating its symptoms have improved vastly but many medicines still use quinine at its base.

A lot of tonic waters available to buy do not use real quinine, using artificially synthesised substitutes instead. At Fever-Tree, we not only use real quinine but the highest-quality, medicinal-grade quinine from a small producer on the border of Rwanda and the Democratic Republic of Congo.

https://fever-tree.com/en_US/article/quinine-and-coronavirus