https://en.wikipedia.org/wiki/Mary_Matalin
She rose quickly, as an aide to Richard Bond and Chief of Staff to RNC co-Chairperson Betty Heitman in 1985. A year later, Matalin gained national attention when she joined George H. W. Bush's 1988 presidential campaign, working as both Deputy Political Director and Midwest Regional Political Director in the primaries. After the election, Matalin was appointed Chief of Staff to then RNC Chairman Lee Atwater. In that capacity, she would in effect run the RNC for nearly a year, as Atwater—his health declining due to an inoperable brain tumor—spent 170 days in the hospital between his diagnosis in early March 1990 and eventual death on March 29, 1991.
In 1992, Matalin served as the deputy campaign manager for political operations on Bush's reelection campaign. Ironically, she served in this role while dating her future husband, James Carville, who was chief strategist for the Clinton campaign.