It refers to the drug unit of police. It's another way of saying fuck the police. Some say it originates from Adam-12 from the 60's 70's show. But, just searched "fuck 12 term" and a pr0nhub link popped up (ain't clicking that shit nigga) that I'm not going to retype here.
Fuck niggers.
Kill yourself nigger.
Every organization that Soros funded should be dismantled and charged with RICO.