Could Gilead Sciences Have an HIV Cure Waiting in the Wings?
Treating COVID-19 is great. But
the real game-changer for Gilead could be in curing HIV.
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the biotech doesn't just have one pipeline candidate in clinical testing that could achieve that goal – it has four.
In January, Gilead licensed a portfolio of broadly neutralizing antibodies (bNAbs) developed by The Rockefeller University. Two of these bNAbs, GS-5423 and GS-2872, are being evaluated in phase 2 testing for treating, preventing, and potentially curing HIV. However, Gilead isn't conducting the clinical studies on its own but is collaborating with Rockefeller.
The big biotech is also evaluating two other potential HIV cures in phase 1 clinical studies. Elipovimab (GS-9722) is a first-in-class bNAb for targeted elimination of HIV-infected cells. Vesatolimod (GS-9620) is a toll-like receptor 7 (TLR7) agonist that has demonstrated potential for curing rhesus monkeys infected with HIV in preclinical testing.
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https://www.fool.com/investing/2020/06/14/could-gilead-sciences-have-an-hiv-cure-waiting-in.aspx